National Hospital Organization, Kyoto Medical Center , Kyoto , Japan.
Asian Society of Gynecologic Oncology , Seoul , Korea.
Cancer Invest. 2019;37(9):427-431. doi: 10.1080/07357907.2019.1661428. Epub 2019 Sep 9.
The genome represents a design for creating the body, with each one being different. In cancer genomic medicine, many genes are simultaneously examined using mainly cancer tissues (the oncogene panel test), and gene mutations are revealed. Cancer treatments are then initiated according to each individual's constitution and medical condition based on gene mutations. A system for cancer genome medical treatment is currently being developed. In the treatment of several types of cancer, the "oncogene test with an oncogene companion diagnosis" is already being performed as a standard test using cancer tissue to detect one or more gene mutations. On June 1, 2019, the cancer gene panel test was covered by the national health insurance system in Japan, and a system to initiate cancer genome medical treatment has begun. The prospects and problems associated with cancer genome medicine are discussed herein.
基因组代表了创造身体的设计蓝图,每个人的基因组都是不同的。在癌症基因组医学中,主要使用癌症组织同时检查许多基因(肿瘤基因panel 检测),并揭示基因的突变。然后根据每个个体的体质和基因突变的情况,开始进行癌症治疗。目前正在开发癌症基因组医疗系统。在几种类型的癌症的治疗中,已经使用癌症组织进行“肿瘤基因检测与肿瘤基因伴随诊断”作为标准检测,以检测一个或多个基因的突变。2019 年 6 月 1 日,日本国家医保体系覆盖了癌症基因panel 检测,癌症基因组医疗开始启动。本文讨论了癌症基因组医学的前景和问题。