Departments of Pediatric Surgery and Obstetrics, Gynecology & Reproductive Sciences, McGovern Medical School at the University of Texas Health Science Center at Houston and Children's Memorial Hermann Hospital, Houston, TX, United States.
Departments Obstetrics, Gynecology & Reproductive Sciences and Pediatric Surgery, Division of Maternal-Fetal Medicine, McGovern Medical School at the University of Texas Health Science Center at Houston and Children's Memorial Hermann Hospital, Houston, TX, United States.
Semin Perinatol. 2020 Feb;44(1):151164. doi: 10.1053/j.semperi.2019.07.003. Epub 2019 Jul 30.
Congenital diaphragmatic hernia (CDH) remains one of the most elusive birth defects to treat. Despite greater knowledge of disease and advances in technology, approximately one-third of CDH children born today still die. Consequently, clinicians and researchers have struggled to find the optimal treatment strategies for CDH. Without further innovations in postnatal treatment, many have focused an antenatal approach to improve pulmonary function. Fetoscopic Endoluminal Tracheal Occlusion (FETO) for CDH has evolved to the bedside after decades of research. While still under clinical investigation, FETO remains a promising adjunct to the treatment of CDH.
先天性膈疝 (CDH) 仍然是最难治疗的出生缺陷之一。尽管对疾病的了解更多，技术也有所进步，但如今出生的 CDH 患儿仍有约三分之一死亡。因此，临床医生和研究人员一直在努力寻找 CDH 的最佳治疗策略。如果不在产后治疗方面取得进一步创新，许多人已经将注意力集中在产前方法上，以改善肺功能。数十年来的研究使胸腔镜腔内气管阻塞术 (FETO) 应用于临床。虽然仍处于临床研究阶段，但 FETO 仍然是 CDH 治疗的一种很有前途的辅助手段。
