Feleke Berhanu Elfu
Department of Epidemiology and Biostatistics, University of Bahir Dar, Bahir Dar, Ethiopia.
Clin Nutr ESPEN. 2019 Oct;33:139-142. doi: 10.1016/j.clnesp.2019.06.005. Epub 2019 Jun 22.
The objectives of this study were to estimate the prevalence and identify the determinants of nutritional status in Leishmaniasis patients and their family members.
A comparative cross-sectional study design was implemented among patients visiting the Kala-azar treatments centers in Amhara region. Systematic sampling technique was used to select the Kala-azar patients and simple random sampling technique was used to select the family members. Data were collected using interview, measuring anthropometric indicators and collecting the stool and blood samples. Descriptive statistics were used to estimate the proportion of malnutrition among the Kala-azar patients and their family members. Binary logistic regression was used to identify the determinants of malnutrition. 762 visceral leishmaniasis patients and 2287 family members were included.
The prevalence of underweight among visceral leishmaniasis patients was 82% [95% CI: 79%-85%], the prevalence of underweight among visceral leishmaniasis family members was 48.3% [95% CI: 46%-50%]. The mean hemoglobin concentration of visceral leishmaniasis patients was 9.46 g/dl and the mean hemoglobin concentration of visceral leishmaniasis patients' family members was 11.46 g/dl. The nutritional status of kala-azar patients was affected by intestinal parasite (AOR: 15.65 [95% CI; 779-31.44]), male sex (AOR: 2.15 [95%CI; 1.12-4.12]), literacy (AOR: 0.4 [AOR; 0.2-0.84]), urban residence (AOR: 0.46 [95%; 0.23-0.92]), income (AOR: 3.44 [95% CI; 1.76-6.74]).
The visceral leishmaniasis treatments guideline should consider supplying nutrients including iron as part of the curative intervention.
本研究的目的是估计利什曼病患者及其家庭成员营养状况的患病率并确定其决定因素。
在阿姆哈拉地区访问黑热病治疗中心的患者中实施了一项比较横断面研究设计。采用系统抽样技术选择黑热病患者，采用简单随机抽样技术选择家庭成员。通过访谈、测量人体测量指标以及采集粪便和血液样本收集数据。使用描述性统计来估计黑热病患者及其家庭成员中营养不良的比例。使用二元逻辑回归来确定营养不良的决定因素。纳入了762例内脏利什曼病患者和2287名家庭成员。
内脏利什曼病患者中体重不足的患病率为82%[95%置信区间：79%-85%]，内脏利什曼病患者家庭成员中体重不足的患病率为48.3%[95%置信区间：46%-50%]。内脏利什曼病患者的平均血红蛋白浓度为9.46g/dl，内脏利什曼病患者家庭成员的平均血红蛋白浓度为11.46g/dl。黑热病患者的营养状况受肠道寄生虫（比值比：15.65[95%置信区间；7.79-31.44]）、男性性别（比值比：2.15[95%置信区间；1.12-4.12]）、识字率（比值比：0.4[比值比；0.2-0.84]）、城市居住（比值比：0.46[95%；0.23-0.92]）、收入（比值比：3.44[95%置信区间；1.76-6.74]）影响。
内脏利什曼病治疗指南应考虑提供包括铁在内的营养物质作为治疗干预的一部分。
