Waqas Qazi Ahmed, Abdullah Hafez Mohammad Ammar, Khan Uzma Ikhtiar, Oliver Tony
Internal Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, South Dakota, USA.
Internal Medicine, Khyber Medical College, Peshawar, Pakistan.
BMJ Case Rep. 2019 Aug 26;12(8):e230229. doi: 10.1136/bcr-2019-230229.
Human cytomegalovirus (CMV) is a double-stranded DNA virus that can cause widespread severe infection in immunocompromised individuals but is more typically a subclinical infection in immunocompetent individuals. Rarely, it can cause a serious infection in immunocompetent individuals. Here, we describe a 36-year-old otherwise healthy male who presented with fever, cough and malaise who was diagnosed with CMV pneumonia. He made a rapid recovery after initiation of ganciclovir and has been doing well on follow-up visits. We performed a comprehensive review of CMV pneumonia in immunocompetent individuals and have summarised the prior 16 reported cases of CMV pneumonia in immunocompetent patients. This article highlights the importance of considering CMV as a cause of pneumonia even in immunocompetent individuals, especially when the more common causes have been excluded. Early diagnosis allows prompt treatment and potentially complete recovery.
人巨细胞病毒（CMV）是一种双链DNA病毒，可在免疫功能低下的个体中引起广泛的严重感染，但在免疫功能正常的个体中通常为亚临床感染。在免疫功能正常的个体中，它很少会引起严重感染。在此，我们描述一名36岁的健康男性，他出现发热、咳嗽和不适症状，被诊断为CMV肺炎。在开始使用更昔洛韦治疗后，他迅速康复，随访期间情况良好。我们对免疫功能正常个体的CMV肺炎进行了全面回顾，并总结了之前报道的16例免疫功能正常患者的CMV肺炎病例。本文强调，即使在免疫功能正常的个体中，尤其是在排除了更常见的病因后，也应考虑CMV作为肺炎病因的重要性。早期诊断有助于及时治疗，并有可能实现完全康复。
