Department of Cardiology, Bergama State Hospital, Islamsaray Mh. Adnan Menderes Bul. No. 221, Bergama, Izmir, Turkey.
Curr Hypertens Rep. 2019 Aug 26;21(10):73. doi: 10.1007/s11906-019-0982-3.
Hypertension cause damage in cardiac structure and induce pathological myocardial fibrosis that leads to hypertensive cardiomyopathy. A narrow fragmented QRS complex (fQRS) is associated with myocardial fibrosis and scar tissue in various cardiovascular diseases. It is also associated with myocardial fibrosis in hypertensive patients even in the absence of any structural heart diseases. This article aimed to demonstrate importance and usefulness of fQRS in hypertensive patients.
Current evidence suggest that the frequency of fQRS is significantly higher in hypertensive patients compared to normotensives. Also, fQRS seems to be a predictor of left ventricular hypertrophy, increased systolic blood pressure, non-dipping, deterioration of the left ventricular geometry, and worse systolic and diastolic functions in hypertensive patients. As a simple and easy detectable electrocardiographic finding, fQRS may indicate myocardial fibrosis, uncontrolled blood pressure, and deteriorated cardiac structure in hypertensive patients even in the absence of other structural heart diseases, and may also be useful to predict high-risk hypertensives.
高血压导致心脏结构损伤，并引起病理性心肌纤维化，进而导致高血压性心肌病。在各种心血管疾病中，窄 QRS 碎裂波（fQRS）与心肌纤维化和瘢痕组织相关。在没有任何结构性心脏病的情况下，高血压患者也存在 fQRS，它与心肌纤维化相关。本文旨在阐述 fQRS 在高血压患者中的重要性和实用性。
目前的证据表明，与血压正常者相比，高血压患者 fQRS 的发生率明显更高。此外，fQRS 似乎是高血压患者左心室肥厚、收缩压升高、非杓型血压、左心室几何形状恶化以及收缩和舒张功能恶化的预测因子。fQRS 作为一种简单且易于检测的心电图表现，即使在没有其他结构性心脏病的情况下，也可能提示高血压患者存在心肌纤维化、血压控制不佳和心脏结构恶化，并且可能有助于预测高危高血压患者。
