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土耳其单中心研究:睾丸癌患者的生育力。

Fertility in testicular cancer patients: a single-centre study in Turkey.

机构信息

Department of Medical Oncology, Akdeniz Universty Hospital, Antalya, Turkey.

Faculty of Nursing, Akdeniz University, Antalya, Turkey.

出版信息

Int J Clin Oncol. 2020 Mar;25(3):495-500. doi: 10.1007/s10147-019-01534-7. Epub 2019 Aug 26.

Abstract

BACKGROUND

Testicular cancer is a rare type of cancer in males. Since the disease is seen in young men and long-term survival is ensured following a high treatment success rate, fertility in testicular cancer patients is much more important. Prior to commencement of cancer treatment, patients are given counselling with regard to infertility and sexual function, and sperm banking is commonly carried out. The aim of this study was to assess the fertility status prior to and following treatment of monitored testicular cancer patients whose treatment had been completed.

METHODS

110 patients diagnosed with and treated for testicular cancer at the Medical Oncology Clinic at Akdeniz University during the years 2000-2016 were evaluated for the study. The patients' disease and treatment information was obtained from their records. The patients' characteristics and fertility statuses were determined by means of interviews with the patients.

RESULTS

The median age of the patients was 36 (20-73) and 39.1% of them (n = 43) were aged between 30 and 39. The average length of follow-up was 6.20 ± 3.36 (2-17) years. It was determined that 42.7% of the patients had banked sperm following diagnosis and that 74.5% of them had received counselling. Following treatment, 33 patients (30%) fathered children. The average time taken to father children after treatment was 3 years.

CONCLUSION

In testicular cancer patients, fatherhood is achieved spontaneously or with the cryopreservation process. Counselling plays an important role at the time of diagnosis. It is essential that health professionals in oncology clinics give counselling about fertility in testicular cancer.

摘要

背景

睾丸癌是男性中一种罕见的癌症。由于这种疾病发生在年轻男性身上,且治疗成功率高,能够确保长期生存,因此睾丸癌患者的生育能力更为重要。在开始癌症治疗之前,患者会接受有关不育和性功能的咨询,并通常进行精子冷冻保存。本研究旨在评估已完成治疗的监测性睾丸癌患者治疗前后的生育状况。

方法

评估了 2000 年至 2016 年期间在阿克登兹大学医学肿瘤学诊所诊断和治疗的 110 例睾丸癌患者。从他们的记录中获得了患者的疾病和治疗信息。通过与患者面谈确定了患者的特征和生育状况。

结果

患者的中位年龄为 36(20-73)岁,其中 39.1%(n=43)年龄在 30-39 岁之间。平均随访时间为 6.20±3.36(2-17)年。诊断后,有 42.7%的患者进行了精子冷冻保存,有 74.5%的患者接受了咨询。治疗后,有 33 名患者(30%)生育了孩子。治疗后生育孩子的平均时间为 3 年。

结论

在睾丸癌患者中,生育能力是通过自然或冷冻保存过程实现的。咨询在诊断时起着重要作用。肿瘤学诊所的卫生专业人员必须就睾丸癌的生育能力提供咨询。

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