Gursu Hazım Alper, Cetin Ibrahim Ilker, Azak Emine, Kibar Ayse Esin, Surucu Murat, Orgun Ali, Pamuk Utku
Department of Pediatric Cardiology, Ankara Child Health and Diseases, Hematology Oncology Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Echocardiography. 2019 Sep;36(9):1666-1674. doi: 10.1111/echo.14449. Epub 2019 Aug 26.
The aim was to evaluate the role of tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE), to identify myocardial dysfunction, and to evaluate myocardial segmental deformation in acute viral myocarditis.
Twenty-one patients and twelve healthy children were studied prospectively. The TDI and STE were performed before and after treatment. The myocardial velocities (S , E , and A ) and time intervals (isovolumic contraction, isovolumic relaxation, and ejection times [ET]) at interventricular septum (IVS), left, and right ventricular basal segments were examined by TDI. The left ventricular global longitudinal strain (LVGLS) and strain rate (LVGLSR), left ventricular global circumferential strain (LVGCS) and strain rate (LVGCSR), and right ventricular global longitudinal strain (RVGLS) and strain rate (RVGLSR) were examined by STE.
S and E at IVS and at LV, ET at IVS, ET at RV, ET at LV were significantly lower in patients before treatment than controls. LVGLS, LVGLSR, LVGCS, LVGCSR, RVGLS, RVGLSR were significantly decreased in patients before treatment than controls. There was significant improvement for LVGLS, LVGLSR, LVGCS, LVGCSR, and RVGLS in patients after treatment. S , E , and A at LV were significantly lower in patients before treatment than in patients after treatment. In spite of improvements, S , E , and ET at IVS, LVGLS, LVGLSR, LVGCS, LVGCSR were significantly lower in patients after treatment than controls.
The TDI and STE were useful methods for detection of early myocardial dysfunction and evaluation of treatment outcomes in acute viral myocarditis.
旨在评估组织多普勒成像（TDI）和斑点追踪超声心动图（STE）在识别急性病毒性心肌炎心肌功能障碍及评估心肌节段变形中的作用。
前瞻性研究了21例患者和12名健康儿童。在治疗前后进行TDI和STE检查。通过TDI检查室间隔（IVS）、左心室和右心室基底段的心肌速度（S、E和A）以及时间间期（等容收缩期、等容舒张期和射血时间[ET]）。通过STE检查左心室整体纵向应变（LVGLS）和应变率（LVGLSR）、左心室整体圆周应变（LVGCS）和应变率（LVGCSR）以及右心室整体纵向应变（RVGLS）和应变率（RVGLSR）。
治疗前患者IVS和左心室的S和E、IVS的ET、右心室的ET、左心室的ET均显著低于对照组。治疗前患者的LVGLS、LVGLSR、LVGCS、LVGCSR、RVGLS、RVGLSR均显著低于对照组。治疗后患者的LVGLS、LVGLSR、LVGCS、LVGCSR和RVGLS有显著改善。治疗前患者左心室的S、E和A显著低于治疗后患者。尽管有所改善，但治疗后患者IVS的S、E和ET、LVGLS、LVGLSR、LVGCS、LVGCSR仍显著低于对照组。
TDI和STE是检测急性病毒性心肌炎早期心肌功能障碍及评估治疗效果的有用方法。
