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深部子宫内膜异位症经阴道超声在有子宫内膜异位症体征和症状患者中的检查中的应用:成本分析。

Deep endometriosis transvaginal ultrasound in the workup of patients with signs and symptoms of endometriosis: a cost analysis.

机构信息

Acute Gynaecology, Early Pregnancy and Advanced Endosurgery Unit, Sydney Medical School Nepean, University of Sydney, Nepean Hospital, Sydney, NSW, Australia.

School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Qld, Australia.

出版信息

BJOG. 2019 Nov;126(12):1499-1506. doi: 10.1111/1471-0528.15917. Epub 2019 Sep 18.

Abstract

OBJECTIVE

Deep endometriosis transvaginal ultrasound (DE TVS) is accurate in the detection of ovarian endometriosis and DE; however, realisation of its full potential and utilisation remains variable. As such, patients may require a two-step surgical approach (diagnostic followed by therapeutic laparoscopy) or experience incomplete surgical treatment. Besides the clinical implications, the economic impact of a two-step approach to diagnosis and treatment on the healthcare system is likely to be significant. We aim to compare the economic costs of two diagnostic models of care for patients with potential endometriosis.

DESIGN

Cost analysis using Markov model with 12-month time horizon comparing the economic costs of two diagnostic models.

SETTING

The study used a hypothetical population of 1000 women visiting a public tertiary gynaecology clinic.

POPULATION

Women with potential endometriosis. Estimates for endometriosis prevalence and severity were drawn from local Australian hospital data.

METHODS

The conventional model (M1) includes the basic TVS and diagnostic laparoscopy. The novel model (M2) includes the DE TVS. Probabilistic sensitivity analysis was conducted to capture the uncertainty in the information used to populate the models.

MAIN OUTCOME MEASURE

Changes to government, health-service and patient costs with the adoption of the DE TVS compared with standard diagnostic methods. Costs are given in Australian dollars (AU$) and also in pound sterling (£).

RESULTS

The total annual cost of the novel model (M2) is AU$12,547,724.03 (£6,826,673.63), cheaper than the conventional model (M1), which cost AU$13,472,161.67 (£7,329,620.15).

CONCLUSIONS

For a population of 1000 women, the integration of the DE TVS may save healthcare costs of AU$924,437 (£502,946.17) annually.

TWEETABLE ABSTRACT

An endometriosis-focused ultrasound may negate a two-step surgery pathway, including diagnostic surgery, and save healthcare money.

摘要

目的

深部子宫内膜异位症经阴道超声(DE TVS)在卵巢子宫内膜异位症和深部浸润型子宫内膜异位症的检测中具有较高的准确性;然而,其充分应用和利用仍存在差异。因此,患者可能需要两步手术(先诊断,后行腹腔镜治疗),或者经历不完整的手术治疗。除了临床意义之外,两步诊断和治疗方法对医疗保健系统的经济影响也可能是巨大的。我们旨在比较两种潜在子宫内膜异位症患者护理诊断模型的经济成本。

设计

使用 12 个月时间框架的 Markov 模型进行成本分析,比较两种诊断模型的经济成本。

设置

该研究使用了一个来自公立三级妇科诊所的 1000 名女性的假设人群。

人群

患有潜在子宫内膜异位症的女性。子宫内膜异位症的患病率和严重程度的估计值取自澳大利亚当地医院的数据。

方法

传统模型(M1)包括基本 TVS 和诊断性腹腔镜检查。新模型(M2)包括 DE TVS。概率敏感性分析用于捕获用于填充模型的信息中的不确定性。

主要观察指标

与标准诊断方法相比,采用 DE TVS 对政府、医疗服务和患者成本的变化。成本以澳元(AU$)和英镑(£)表示。

结果

新模型(M2)的年总成本为 12547724.03 澳元(6829673.63 英镑),低于传统模型(M1)的 13472161.67 澳元(7329620.15 英镑)。

结论

对于 1000 名女性的人群,深部子宫内膜异位症超声的整合可能每年节省医疗保健成本 924437 澳元(5029461.77 英镑)。

推特摘要

聚焦于子宫内膜异位症的超声检查可能会否定两步手术的途径,包括诊断性手术,并节省医疗保健费用。

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