Tokgöz Sibel Alicura, Saylam Güleser, Bayır Ömer, Keseroğlu Kemal, Toptaş Gökhan, Çadallı Tatar Emel, Akın İstemihan, Korkmaz Mehmet Hakan
Department of Otorhinolaryngology, University of Health Sciences Dışkapı Yıldırım Beyazıt Training and Research Hospital , Ankara , Turkey.
Acta Otolaryngol. 2019 Oct;139(10):930-933. doi: 10.1080/00016489.2019.1655588. Epub 2019 Aug 27.
Head and neck paragangliomas are slowly growing benign tumors and they originate from specialized neural crest cells. This study aimed to express the safety of paraganglioma surgery regarding complications, treatment, and outcomes of patients with head and neck glomus tumors. Medical records of patients who were operated because of head and neck paraganglioma between 2006 and 2016 were reviewed. The study group consisted of 49 patients (M/F: 6/43). The patients were distributed as follows: 22 glomus caroticum (GC) (44.8%), 8 glomus jugulare (GJ) (16.3%), 10 glomus tympanicum (GT) (20.4%), 4 glomus vagale (GV) (8.1%), 2 GC + GV (4%), 2 bilateral GC (4%) and 1 thyroidal glomus tumor (2%). All GC and GV tumors were resected via cervical approach. Three of GJ tumors were resected through transmastoid approach while five of them were resected through both transmastoid and cervical approach. Nine GT tumors were resected via transmastoid approach. One patient received cyberknife. Thyroid paraganglioma was diagnosed incidentally after total thyroidectomy. Mean follow-up period was 61.92 ± 35.11 months (1-124 m). The choice of treatment depends on the size, location and biologic activity of tumor as well as the physical condition of the patient. Our results show that glomus tumors can be resected with low mortality and morbidity rates due to developing imaging and microsurgical methods.
头颈部副神经节瘤是生长缓慢的良性肿瘤，起源于特殊的神经嵴细胞。本研究旨在阐述头颈部球瘤患者副神经节瘤手术在并发症、治疗及预后方面的安全性。回顾了2006年至2016年间因头颈部副神经节瘤接受手术治疗患者的病历。研究组包括49例患者（男/女：6/43）。患者分布如下：22例颈动脉体瘤（GC）（44.8%），8例颈静脉球瘤（GJ）（16.3%），10例鼓室球瘤（GT）（20.4%），4例迷走神经球瘤（GV）（8.1%），2例GC+GV（4%），2例双侧GC（4%）和1例甲状腺球瘤（2%）。所有GC和GV肿瘤均通过颈部入路切除。3例GJ肿瘤通过经乳突入路切除，5例通过经乳突和颈部联合入路切除。9例GT肿瘤通过经乳突入路切除。1例患者接受了射波刀治疗。甲状腺副神经节瘤在全甲状腺切除术后偶然诊断。平均随访期为61.92±35.11个月（1 - 124个月）。治疗方案的选择取决于肿瘤的大小、位置、生物学活性以及患者的身体状况。我们的结果表明，由于影像学和显微外科技术的发展，球瘤能够以较低的死亡率和发病率进行切除。
