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甲氯芬酯短期给药对大鼠计数行为的急性影响。

Acute effects of centrophenoxine short term administration on counting behavior in rats.

作者信息

Idrobo F, Mostofsky D I, Nandy K

机构信息

Boston University, Department of Psychology, MA 02215.

出版信息

Int J Neurosci. 1988 Oct;42(3-4):309-13. doi: 10.3109/00207458808991606.

Abstract

This experiment assessed the effects of Centrophenoxine on counting behavior in rats. Intraperitoneal Centrophenoxine injections were given to rats before training on a 20-fixed-consecutive-number schedule of reinforcement. The primary measure was the number of consecutive lever presses. After Centrophenoxine injections, the number of consecutive lever presses was lower relative to baseline measures. The measures of variability indicated that although the consecutive number of responses was lower this could not be accounted for in terms of run length variability. The behavioral pattern produced by the injections was discussed in terms of possible shortterm physiological effects that affect performance.

摘要

本实验评估了氯酯醒对大鼠计数行为的影响。在对大鼠进行固定连续20次强化训练之前,给它们腹腔注射氯酯醒。主要测量指标是连续按压杠杆的次数。注射氯酯醒后,连续按压杠杆的次数相对于基线测量值较低。变异性测量表明,尽管连续反应次数较低,但这不能用反应长度变异性来解释。根据可能影响行为表现的短期生理效应,对注射产生的行为模式进行了讨论。

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