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在三维患者特异性质量保证计划中对Dolphin剂量测定法的验证

Validation of Dolphin dosimetry in three dimensional patient-specific quality assurance programme.

作者信息

Puzhakkal Niyas, Kochunny Abdullah Kallikuzhiyil, Makuny Dinesh, Krishnan M P Arun, Poyil Ranjith C, Raveendran Vysakh

机构信息

Department of Medical Physics, MVR Cancer Centre & Research Institute, Kozhikode, Kerala, India.

Department of Physics, Farook College, Kozhikode, Kerala, India.

出版信息

Rep Pract Oncol Radiother. 2019 Sep-Oct;24(5):481-490. doi: 10.1016/j.rpor.2019.07.006. Epub 2019 Aug 12.

Abstract

AIM

The aim of this study is to commission and validate Dolphin-Compass dosimetry as a patient-specific Quality Assurance (QA) device.

BACKGROUND

The advancement of radiation therapy in terms of highly conformal delivery techniques demands a novel method of patient-specific QA. Dolphin-Compass system is a dosimetry solution capable of doing different QA in radiation therapy.

MATERIALS AND METHODS

Dolphin, air-vented ionization detector array mounted on Versa-HD Linear Accelerator (LINAC) was used for measurements. The Compass is a dose computation algorithm which requires modelling of LINAC head similar to other Treatment Planning Systems (TPS). The dosimetry system was commissioned after measuring the required beam data. The validation was performed by comparison of treatment plans generated in Monaco TPS against the measurement data. Different types of simple, complex, static and dynamic radiation fields and highly conformal treatment plans of patients were used in this study.

RESULTS

For all field sizes, point doses obtained from Dolphin-Compass dosimetry were in good agreement with the corresponding TPS calculated values in most of the regions, except the penumbra, outside field and at build-up depth. The results of gamma passing rates of measurements by using different Multi-leaf Collimator patterns and Intensity Modulated Radiation Therapy fluence were also found to be in good correlation with the corresponding TPS values.

CONCLUSIONS

The commissioning and validation of dosimetry was performed with the help of various fields, MLC patterns and complex treatment plans. The present study also evaluated the efficiency of the 3D dosimetry system for the QA of complex treatment plans.

摘要

目的

本研究旨在启用并验证Dolphin-Compass剂量测定法作为一种针对患者的质量保证(QA)设备。

背景

放射治疗在高适形递送技术方面的进步需要一种针对患者的新型QA方法。Dolphin-Compass系统是一种能够在放射治疗中进行不同QA的剂量测定解决方案。

材料与方法

使用安装在Versa-HD直线加速器(LINAC)上的带通气孔的空气电离探测器阵列Dolphin进行测量。Compass是一种剂量计算算法,需要对LINAC机头进行建模,类似于其他治疗计划系统(TPS)。在测量所需的射束数据后启用剂量测定系统。通过将Monaco TPS生成的治疗计划与测量数据进行比较来进行验证。本研究使用了不同类型的简单、复杂、静态和动态辐射野以及患者的高适形治疗计划。

结果

对于所有射野尺寸,除了半影区、射野外和建成深度处,Dolphin-Compass剂量测定法获得的点剂量在大多数区域与相应的TPS计算值吻合良好。使用不同的多叶准直器模式和调强放射治疗注量进行测量的伽马通过率结果也与相应的TPS值具有良好的相关性。

结论

借助各种射野、MLC模式和复杂治疗计划进行了剂量测定的启用和验证。本研究还评估了3D剂量测定系统对复杂治疗计划进行QA的效率。

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