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DEFGEL和PAGAT公式与MRI采集配对的剂量学比较。

Dosimetric comparison of DEFGEL and PAGAT formulae paired with an MRI acquisition.

作者信息

Matrosic Charles, McMillan Alan, Holmes James, Bednarz Bryan, Culberson Wesley

机构信息

The University of Wisconsin School of Medicine and Public Health, University of Wisconsin - Madison, Department of Medical Physics, Madison, WI.

The University of Wisconsin School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiology, Madison, WI.

出版信息

J Phys Conf Ser. 2017;847. doi: 10.1088/1742-6596/847/1/012012. Epub 2017 Jun 5.

DOI:10.1088/1742-6596/847/1/012012
PMID:31452665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6709699/
Abstract

Normoxic Polyacrylamide Gels, or nPAGs, are 3D gel dosimeters that measure dose through the process of radiation-induced polymerization. Two nPAG formulae are DEFGEL and PAGAT, which are very similar, but differ mainly due to different weight fractions of monomers. The dosimetric resolutions of the two formulae when paired with a Spin-Echo (SE) MRI sequence and a monoexponential fit were compared over a range of 0-15 Gy. It was found that in the dose range 0-6 Gy the PAGAT formula generally showed a much finer dose resolution, while the DEFGEL formula showed a finer resolution from 8-15 Gy.

摘要

常氧聚丙烯酰胺凝胶(nPAGs)是一种三维凝胶剂量计,通过辐射诱导聚合过程来测量剂量。两种nPAG配方分别是DEFGEL和PAGAT,它们非常相似,但主要因单体重量分数不同而有所差异。在0 - 15 Gy范围内,比较了这两种配方与自旋回波(SE)MRI序列和单指数拟合相结合时的剂量分辨率。结果发现,在0 - 6 Gy剂量范围内,PAGAT配方通常显示出更精细的剂量分辨率,而DEFGEL配方在8 - 15 Gy范围内显示出更精细的分辨率。

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Phys Med Biol. 2013 Jan 7;58(1):19-42. doi: 10.1088/0031-9155/58/1/19. Epub 2012 Dec 6.
2
A novel methodology for 3D deformable dosimetry.一种用于 3D 变形剂量学的新方法。
Med Phys. 2012 Apr;39(4):2203-13. doi: 10.1118/1.3694107.
3
The fundamental radiation properties of normoxic polymer gel dosimeters: a comparison between a methacrylic acid based gel and acrylamide based gels.常氧聚合物凝胶剂量计的基本辐射特性:基于甲基丙烯酸的凝胶与基于丙烯酰胺的凝胶之间的比较。
Phys Med Biol. 2006 Feb 7;51(3):653-73. doi: 10.1088/0031-9155/51/3/012. Epub 2006 Jan 19.
4
Investigation of the PAGAT polymer gel dosimeter using magnetic resonance imaging.使用磁共振成像对PAGAT聚合物凝胶剂量计进行研究。
Phys Med Biol. 2005 Aug 21;50(16):3875-88. doi: 10.1088/0031-9155/50/16/015. Epub 2005 Aug 2.
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