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炎症性关节炎合并炎症性肠病:两例病例报告

Inflammatory arthritis complicated by inflammatory bowel disease: two case reports.

作者信息

Cengiz Damla, Gürçay Eda, Karaahmet Özgür Zeliha, Karaahmet Fatih, Umay Ebru, Çakcı Aytül

机构信息

Department of Physical Medicine and Rehabilitation, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.

Department of Gastroenterology, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.

出版信息

Turk J Phys Med Rehabil. 2017 Apr 21;63(3):266-271. doi: 10.5606/tftrd.2017.23169. eCollection 2017 Jun.

Abstract

Coexistence of inflammatory arthritis disease and inflammatory bowel disease (IBD) is often considered to be relatively rare, and the underlying mechanisms of the association between them remain unclear. Herein, we report two cases of IBD which occurred during the course of inflammatory arthritis disease. The first case had psoriatic arthritis (PsA) for two and a half years complicated by Crohn's disease and accompanied by inactive carrier state of hepatitis B. The second case had rheumatoid arthritis (RA) complicated by ulcerative colitis four years after the onset of RA. In both cases, colonoscopy was performed, and their clinical presentations improved with a multidisciplinary approach. In the event of complaints related to the gastrointestinal tract in patients with PsA or RA, IBD should be kept in mind, and the clinical evaluation and multidisciplinary interventions should be planned to control the underlying autoimmune process.

摘要

炎性关节炎疾病与炎性肠病(IBD)并存通常被认为相对罕见,它们之间关联的潜在机制仍不清楚。在此,我们报告两例在炎性关节炎疾病过程中发生的IBD病例。第一例患有银屑病关节炎(PsA)两年半,并发克罗恩病,同时伴有乙肝病毒携带状态。第二例在类风湿关节炎(RA)发病四年后并发溃疡性结肠炎。两例均进行了结肠镜检查,通过多学科方法其临床表现均有改善。对于患有PsA或RA且出现胃肠道相关症状的患者,应考虑IBD的可能,并应规划临床评估和多学科干预措施以控制潜在的自身免疫过程。

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