Cruz Vitor Alves, Yamaguchi Lúcio, Ribeiro Carolina Nazeozeno, Magalhães Vanessa de Oliveira, Rego Jozelia, Silva Nilzio Antonio da
Serviço de Reumatologia Ambulatório de Artrite Reumatoide, Hospital das Clínicas, Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, GO, Brazil.
Rev Bras Reumatol. 2012 Aug;52(4):648-50.
Ulcerative colitis is an autoimmune disorder of unknown etiology. Although the large intestine is the major focus of autoimmunity, resulting in chronic diarrhea, that is actually a systemic disease, with numerous extraintestinal manifestations, such as articular involvement. The frequent association of a number of autoimmune diseases in the same patient has been described. However, the coexistence of ulcerative colitis and rheumatoid arthritis is rare. The authors report a case of ulcerative colitis associated with rheumatoid arthritis, in which colitis occurred 12 years before the onset of inflammatory arthropathy.
溃疡性结肠炎是一种病因不明的自身免疫性疾病。虽然大肠是自身免疫的主要靶点，导致慢性腹泻，但它实际上是一种全身性疾病，有许多肠外表现，如关节受累。同一患者常出现多种自身免疫性疾病的关联已被描述。然而，溃疡性结肠炎和类风湿关节炎并存的情况很少见。作者报告了一例溃疡性结肠炎合并类风湿关节炎的病例，其中结肠炎在炎性关节病发作前12年就已出现。
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