Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Canada.
Menopause. 2019 Sep;26(9):1031-1037. doi: 10.1097/GME.0000000000001358.
Specialized interdisciplinary menopause clinics in Edmonton provide care for women suffering from severe menopausal symptoms. Our objectives were to evaluate changes over time in patient-reported menopause symptoms and quality of life (QOL) in a cohort of clinic patients, compared to a cohort of women recruited from the clinic waitlists.
We conducted a prospective study of consecutive new patients in two clinics. Consenting women completed a generic menopause symptom severity questionnaire (MSSQ) and the menopause-specific quality of life (MENQOL) questionnaire at their first clinic and at a follow-up visit. Demographics, medical and obstetric histories, and medication use were extracted from patient charts. Women on the clinics' waitlists were enrolled as controls; corresponding data for baseline and follow-up were collected in mailed-in surveys. Descriptive and paired statistics were used for data analysis. Agreement plot was created to visualize the agreement between MSSQ and MENQOL scores.
A total of 139 women were recruited: 98 attended the clinic and 41 were from the waitlist. Follow-up data were available for 99 women (71 clinic and 28 waitlist). There were no significant differences between clinic and waitlist patient characteristics. Women attending the clinics experienced significant reduction in symptom severity (mean MSSQ scores) and improvement in QOL (reduced MENQOL "bother" scores). Women on the clinic waitlist did not demonstrate significant changes over a similar timeframe. MENQOL correlated well with menopause symptom severity assessment.
Women attending specialized menopause clinics experienced improvement in symptoms and QOL, whereas women on the waitlists did not experience these changes. : Video Summary: Supplemental Digital Content 1, http://links.lww.com/MENO/A418.
埃德蒙顿的专业跨学科更年期诊所为患有严重更年期症状的女性提供护理。我们的目标是评估在两个诊所就诊的队列中，与从诊所候补名单中招募的队列相比，患者报告的更年期症状和生活质量（QOL）随时间的变化。
我们对两个诊所的连续新患者进行了前瞻性研究。同意参加的女性在第一次就诊和随访时完成了通用更年期症状严重程度问卷（MSSQ）和更年期特异性生活质量（MENQOL）问卷。从患者图表中提取人口统计学、医学和产科病史以及药物使用情况。将诊所候补名单上的女性招募为对照组；通过邮寄调查收集基线和随访的相应数据。使用描述性和配对统计数据进行数据分析。创建了一致性图来可视化 MSSQ 和 MENQOL 评分之间的一致性。
共招募了 139 名女性：98 名参加了诊所，41 名来自候补名单。99 名女性（71 名诊所和 28 名候补名单）有随访数据。诊所和候补名单患者的特征无显着差异。参加诊所的女性经历了症状严重程度（平均 MSSQ 评分）的显着降低和生活质量（减少的 MENQOL“困扰”评分）的改善。在类似的时间框架内，候补名单上的女性没有显示出显着变化。MENQOL 与更年期症状严重程度评估相关性良好。
参加专业更年期诊所的女性症状和 QOL 得到改善，而候补名单上的女性则没有经历这些变化。
