Myslicki Francisco A, Rosenberg Andrew E, Chaitowitz Ivan, Subhawong Ty K
From the Musculoskeletal Division, Department of Diagnostic Radiology.
Department of Pathology.
J Comput Assist Tomogr. 2019 Sep/Oct;43(5):793-798. doi: 10.1097/RCT.0000000000000912.
We present 5 cases of intraosseous hibernoma, a rare benign tumor of brown fat. Our literature review reveals that the average age at presentation is 58.6 years, and 69.7% of patients are female. Lesions are most often located in the spine and pelvis. Computed tomography usually demonstrates sclerotic changes, although lesions can be lytic. Magnetic resonance imaging findings include heterogeneous T2 hyperintensity. Technetium 99m-methyl diphosphonate bone scan reveals variable radiotracer uptake, whereas 18F-labeled fluoro-2-deoxyglucose (FDG) PET-CT shows mild uptake. Intraosseous hibernoma should be considered when imaging demonstrates a fat-containing lesion in bone, especially one exhibiting FDG avidity.
我们报告了5例骨内冬眠瘤，这是一种罕见的棕色脂肪良性肿瘤。我们的文献综述显示，发病时的平均年龄为58.6岁，69.7%的患者为女性。病变最常位于脊柱和骨盆。计算机断层扫描通常显示硬化性改变，不过病变也可为溶骨性。磁共振成像表现为T2加权像上信号不均匀增高。锝99m-亚甲基二膦酸盐骨扫描显示放射性示踪剂摄取情况不一，而18F标记的氟代脱氧葡萄糖（FDG）PET-CT显示摄取轻度增高。当影像学显示骨内有含脂肪病变，尤其是表现出FDG摄取的病变时，应考虑骨内冬眠瘤。
