Shaikh Ali, Basha Adil, Ray George, Bishop Justin A, Chhabra Avneesh
UT Southwestern Medical Center, Dallas, TX, 75390-9178, USA.
Johns Hopkins University, Baltimore, MD, USA.
Skeletal Radiol. 2025 May;54(5):1139-1146. doi: 10.1007/s00256-024-04758-5. Epub 2024 Jul 31.
Intraosseous hibernoma is an uncommon presentation of brown adipose tissue benign tumors. Imaging differential diagnoses include bone island, sclerotic metastasis, lymphoma, hemangioma, and sclerotic myeloma. In this report, a 72-year-old patient presented with right hip pain following a fall injury, leading to an extensive diagnostic workup. Initial CT of the pelvis without contrast suggested potential sclerotic metastatic disease. MRI findings could not be definitive. Further assessment with CT-guided biopsy and S-100 immunohistochemical staining confirmed a rare diagnosis of intraosseous hibernoma. This case describes multimodality imaging characteristics of a rare intraosseous hibernoma with discussion of imaging features of differential diagnostic considerations of related benign and malignant bone lesions.
骨内冬眠瘤是棕色脂肪组织良性肿瘤的一种罕见表现形式。影像学鉴别诊断包括骨岛、硬化性转移瘤、淋巴瘤、血管瘤和硬化性骨髓瘤。在本报告中，一名72岁患者因跌倒受伤后出现右髋部疼痛，从而进行了全面的诊断性检查。最初的骨盆平扫CT提示可能为硬化性转移性疾病。MRI检查结果不明确。通过CT引导下活检及S-100免疫组化染色进一步评估，确诊为罕见的骨内冬眠瘤。本病例描述了罕见骨内冬眠瘤的多模态影像学特征，并讨论了相关良性和恶性骨病变鉴别诊断的影像学特征。
