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骨内冬眠瘤:骨科领域中一种具有特殊放射学特征的罕见实体。

Intraosseous Hibernoma: A Rare Entity in Orthopedics With Peculiar Radiological Features.

作者信息

Samargandi Ramy, Le Nail Louis-Romée, de Pinieux Gonzague, Tallegas Matthias, Miquelestorena-Standley Elodie

机构信息

Service d'Orthopédie et Traumatologie, Centre Hospitalier Régional Universitaire (CHRU) de Tours, Tours, FRA.

Orthopedic Surgery Department, Faculty of Medicine, University of Jeddah, Jeddah, SAU.

出版信息

Cureus. 2023 Jun 2;15(6):e39883. doi: 10.7759/cureus.39883. eCollection 2023 Jun.

DOI:10.7759/cureus.39883
PMID:37273679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10237511/
Abstract

Intraosseous hibernoma is a rare benign bone tumor derived from brown fat. It is typically found in the axial skeleton and is more commonly observed in women. It can manifest as a painful lesion or may be incidentally discovered. Intraosseous hibernoma often presents as a sclerotic lesion, although it can also manifest as a lytic lesion. Due to its varied radiographic appearance, it should be considered in the differential diagnosis of bone lesions as it can mimic metastatic lesions as well as other sclerotic and lytic bone lesions. Therefore, obtaining a biopsy of the lesion is crucial for an accurate diagnosis. In this report, we present the clinical, radiological, and histopathological findings of two cases of intraosseous hibernoma and provide a concise overview based on a review of the literature.

摘要

骨内冬眠瘤是一种罕见的源自棕色脂肪的良性骨肿瘤。它通常见于中轴骨骼,女性更为常见。它可表现为疼痛性病变,也可能是偶然发现。骨内冬眠瘤常表现为硬化性病变,不过也可表现为溶骨性病变。由于其多样的影像学表现,在骨病变的鉴别诊断中应考虑到它,因为它可模仿转移性病变以及其他硬化性和溶骨性骨病变。因此,对病变进行活检对于准确诊断至关重要。在本报告中,我们展示了两例骨内冬眠瘤的临床、放射学和组织病理学表现,并在文献回顾的基础上提供了简要概述。

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本文引用的文献

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Intraosseous hibernoma: Two case reports and a review of the literature.骨内冬眠瘤:两例病例报告及文献综述
Radiol Case Rep. 2022 May 9;17(7):2477-2483. doi: 10.1016/j.radcr.2022.01.079. eCollection 2022 Jul.
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Intraosseous hibernoma: A metastatic mimicker to consider on the differential.骨内冬眠瘤:一种在鉴别诊断时需考虑的转移性模仿者。
Radiol Case Rep. 2020 Oct 19;15(12):2677-2680. doi: 10.1016/j.radcr.2020.10.014. eCollection 2020 Dec.
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Intraosseous Hibernoma: Five Cases and a Review of the Literature.骨内冬眠瘤:5例病例报告及文献复习
J Comput Assist Tomogr. 2019 Sep/Oct;43(5):793-798. doi: 10.1097/RCT.0000000000000912.
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Hibernoma Demonstrated on 68Ga-DOTATATE PET/CT.68Ga-DOTATATE PET/CT 显像示冬眠瘤。
Clin Nucl Med. 2019 Jun;44(6):491-493. doi: 10.1097/RLU.0000000000002562.
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Intraosseous hibernoma: case report and tumor characterization.骨内冬眠瘤:病例报告及肿瘤特征分析
BJR Case Rep. 2015 Jul 29;1(3):20150204. doi: 10.1259/bjrcr.20150204. eCollection 2015.
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Rare case of a radiographically occult sacral lesion detected on MRI presenting with intractable back pain.磁共振成像(MRI)检查发现的骶骨隐匿性病变导致顽固性背痛的罕见病例。
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Intraosseous Hibernoma: A Rare and Unique Intraosseous Lesion.骨内冬眠瘤:一种罕见且独特的骨内病变。
J Pathol Transl Med. 2017 Sep;51(5):499-504. doi: 10.4132/jptm.2017.07.28. Epub 2017 Aug 22.
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Incidental brown adipose tissue in bone marrow biopsy.骨髓活检中偶然发现的棕色脂肪组织。
Blood. 2017 Aug 17;130(7):952. doi: 10.1182/blood-2017-04-778563.
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Intraosseous hibernoma: a rare adipocytic bone tumour.骨内冬眠瘤:一种罕见的脂肪细胞性骨肿瘤。
Skeletal Radiol. 2016 Nov;45(11):1565-9. doi: 10.1007/s00256-016-2460-1. Epub 2016 Sep 6.