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狼疮性肠炎误诊为克罗恩病。

Lupus enteritis masquerading as Crohn's disease.

机构信息

Department of Gastroenterology, Anhui Provincial Hospital, Hefei, Anhui, 230001, People's Republic of China.

出版信息

BMC Gastroenterol. 2019 Aug 27;19(1):154. doi: 10.1186/s12876-019-1058-1.

Abstract

BACKGROUND

Systemic lupus erythematosus is an autoimmune disease which can affect multiple organs, resulting in significant mortality and morbidity. Lupus enteritis is one of the rare complications of SLE, defined as vasculitis of the intestinal tract, with supportive biopsy findings and/or image. However, lupus enteritis is seldom confirmed on histology or image and the changes of intestinal mucosa are nonspecific. Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract which affects any part of the gastrointestinal tract. The diagnosis of CD is confirmed by clinical evaluation and a combination of endoscopic, histology, radiology, and/or biochemical investigations.

CASE PRESENTATION

Here we report a rare case of a 71-years-old Chinese male has been diagnosed with lupus enteritis which similar to CD in the aspects of endoscopic, histology, and radiology. So far, there are no relevant cases reported.

CONCLUSIONS

The endoscopic appearance of lupus enteritis is nonspecific, on the basis of our case, the features of lupus enteritis can be described as spacious, clean and no moss ulcers which discontinuous involved all gastrointestinal tract.

摘要

背景

系统性红斑狼疮是一种自身免疫性疾病,可影响多个器官,导致高死亡率和高发病率。狼疮性肠炎是 SLE 的罕见并发症之一,定义为肠道血管炎,具有支持性的活检发现和/或影像学表现。然而,狼疮性肠炎在组织学或影像学上很少得到证实,且肠道黏膜的改变是非特异性的。克罗恩病是一种影响胃肠道任何部位的慢性炎症性疾病。CD 的诊断通过临床评估以及内镜、组织学、影像学和/或生化检查的组合来确认。

病例介绍

本文报告了一例罕见的 71 岁中国男性病例,其在内镜、组织学和影像学方面与 CD 相似。到目前为止,尚无相关病例报告。

结论

狼疮性肠炎的内镜表现是非特异性的,基于我们的病例,狼疮性肠炎的特征可描述为宽阔、清洁、无苔溃疡,且不连续地累及整个胃肠道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/a1cc91c689b3/12876_2019_1058_Fig1_HTML.jpg

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