• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

狼疮性肠炎误诊为克罗恩病。

Lupus enteritis masquerading as Crohn's disease.

机构信息

Department of Gastroenterology, Anhui Provincial Hospital, Hefei, Anhui, 230001, People's Republic of China.

出版信息

BMC Gastroenterol. 2019 Aug 27;19(1):154. doi: 10.1186/s12876-019-1058-1.

DOI:10.1186/s12876-019-1058-1
PMID:31455284
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6712697/
Abstract

BACKGROUND

Systemic lupus erythematosus is an autoimmune disease which can affect multiple organs, resulting in significant mortality and morbidity. Lupus enteritis is one of the rare complications of SLE, defined as vasculitis of the intestinal tract, with supportive biopsy findings and/or image. However, lupus enteritis is seldom confirmed on histology or image and the changes of intestinal mucosa are nonspecific. Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract which affects any part of the gastrointestinal tract. The diagnosis of CD is confirmed by clinical evaluation and a combination of endoscopic, histology, radiology, and/or biochemical investigations.

CASE PRESENTATION

Here we report a rare case of a 71-years-old Chinese male has been diagnosed with lupus enteritis which similar to CD in the aspects of endoscopic, histology, and radiology. So far, there are no relevant cases reported.

CONCLUSIONS

The endoscopic appearance of lupus enteritis is nonspecific, on the basis of our case, the features of lupus enteritis can be described as spacious, clean and no moss ulcers which discontinuous involved all gastrointestinal tract.

摘要

背景

系统性红斑狼疮是一种自身免疫性疾病,可影响多个器官,导致高死亡率和高发病率。狼疮性肠炎是 SLE 的罕见并发症之一,定义为肠道血管炎,具有支持性的活检发现和/或影像学表现。然而,狼疮性肠炎在组织学或影像学上很少得到证实,且肠道黏膜的改变是非特异性的。克罗恩病是一种影响胃肠道任何部位的慢性炎症性疾病。CD 的诊断通过临床评估以及内镜、组织学、影像学和/或生化检查的组合来确认。

病例介绍

本文报告了一例罕见的 71 岁中国男性病例,其在内镜、组织学和影像学方面与 CD 相似。到目前为止,尚无相关病例报告。

结论

狼疮性肠炎的内镜表现是非特异性的,基于我们的病例,狼疮性肠炎的特征可描述为宽阔、清洁、无苔溃疡,且不连续地累及整个胃肠道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/fdffcbee0215/12876_2019_1058_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/a1cc91c689b3/12876_2019_1058_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/1f615016a429/12876_2019_1058_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/1b2b0eb300f5/12876_2019_1058_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/af3954589beb/12876_2019_1058_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/fdffcbee0215/12876_2019_1058_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/a1cc91c689b3/12876_2019_1058_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/1f615016a429/12876_2019_1058_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/1b2b0eb300f5/12876_2019_1058_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/af3954589beb/12876_2019_1058_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efd/6712697/fdffcbee0215/12876_2019_1058_Fig5_HTML.jpg

相似文献

1
Lupus enteritis masquerading as Crohn's disease.狼疮性肠炎误诊为克罗恩病。
BMC Gastroenterol. 2019 Aug 27;19(1):154. doi: 10.1186/s12876-019-1058-1.
2
Coexistence of Crohn's disease and systemic lupus erythematosus: a case report and literature review.克罗恩病与系统性红斑狼疮并存:一例病例报告及文献综述
Eur J Gastroenterol Hepatol. 2020 Sep;32(9):1256-1262. doi: 10.1097/MEG.0000000000001775.
3
Systemic lupus erythematosus complicated by Crohn's disease: a case report and literature review.系统性红斑狼疮并发克罗恩病:病例报告及文献复习。
BMC Gastroenterol. 2012 Dec 5;12:174. doi: 10.1186/1471-230X-12-174.
4
Lupus enteritis as the sole presenting feature of systemic lupus erythematosus: case report and review of the literature.狼疮性肠炎作为系统性红斑狼疮的唯一首发特征:病例报告及文献复习
Paediatr Int Child Health. 2019 Nov;39(4):294-298. doi: 10.1080/20469047.2018.1504430. Epub 2018 Sep 7.
5
Crohn's disease masquerading as systemic lupus erythematosus.
South Med J. 1995 Oct;88(10):1081-3. doi: 10.1097/00007611-199510000-00018.
6
Panenteritis as an Initial Presentation of Systemic Lupus Erythematosus.全肠炎作为系统性红斑狼疮的首发表现
Korean J Gastroenterol. 2016 Feb;67(2):107-11. doi: 10.4166/kjg.2016.67.2.107.
7
[Lupus enteritis as initial manifestation of systemic lupus erythematosus. Report of one case].[狼疮性肠炎作为系统性红斑狼疮的初始表现。1例报告]
Rev Med Chil. 2017 Oct;145(10):1349-1352. doi: 10.4067/S0034-98872017001001349.
8
Lupus enteritis as an initial presentation of systemic lupus erythematosus.狼疮性肠炎作为系统性红斑狼疮的首发表现
Case Rep Gastrointest Med. 2014;2014:962735. doi: 10.1155/2014/962735. Epub 2014 Sep 11.
9
[Case of necrotizing enteritis as the first symptom of systemic lupus erythematosus].[以坏死性小肠炎为系统性红斑狼疮首发症状的病例]
Vutr Boles. 2000;32(2):15-6.
10
Recurrent Abdominal Pain in Systemic Lupus Erythematosus: Concurrent Lupus Enteritis and Lupus Cystitis.系统性红斑狼疮中的复发性腹痛:并发狼疮性肠炎和狼疮性膀胱炎
Am J Med. 2019 May;132(5):e557-e558. doi: 10.1016/j.amjmed.2019.01.021. Epub 2019 Jan 30.

引用本文的文献

1
A Rare Manifestation of Abdominal Pain in Systemic Lupus Erythematosus: A Case Report on Lupus Enterocolitis.系统性红斑狼疮腹痛的罕见表现:狼疮性小肠结肠炎病例报告
Cureus. 2025 Apr 21;17(4):e82750. doi: 10.7759/cureus.82750. eCollection 2025 Apr.
2
An Atypical Initial Manifestation of Systemic Lupus Erythematosus: Lupus Enteritis Accompanied by Intestinal Pseudo-Obstruction and Bilateral Hydronephroureter.系统性红斑狼疮的一种非典型初始表现:狼疮性肠炎伴肠道假性梗阻和双侧肾盂输尿管积水
Cureus. 2023 Dec 16;15(12):e50628. doi: 10.7759/cureus.50628. eCollection 2023 Dec.
3
Rare case of lupus enteritis presenting as colorectum involvement: A case report and review of literature.

本文引用的文献

1
Systemic lupus erythematosus.系统性红斑狼疮。
Lancet. 2014 Nov 22;384(9957):1878-1888. doi: 10.1016/S0140-6736(14)60128-8. Epub 2014 May 31.
2
Tumor necrosis factor-α antibodies (infliximab, adalimumab and certolizumab) in Crohn's disease: systematic review and meta-analysis.肿瘤坏死因子-α 抗体(英夫利昔单抗、阿达木单抗和培塞利珠单抗)在克罗恩病中的应用:系统评价和荟萃分析。
Arch Med Sci. 2013 Oct 31;9(5):765-79. doi: 10.5114/aoms.2013.38670. Epub 2013 Nov 5.
3
Lupus enteritis: from clinical findings to therapeutic management.狼疮性肠炎:从临床发现到治疗管理。
以结直肠受累为表现的狼疮性肠炎罕见病例:一例报告并文献复习
World J Clin Cases. 2023 Dec 6;11(34):8176-8183. doi: 10.12998/wjcc.v11.i34.8176.
4
Use of Mesenchymal Stem Cells in Crohn's Disease and Perianal Fistulas: A Narrative Review.间充质干细胞在克罗恩病和肛周瘘中的应用:叙述性综述。
Curr Stem Cell Res Ther. 2023;18(1):76-92. doi: 10.2174/1574888X16666210916145717.
5
Coexistence of Crohn's disease and systemic lupus erythematosus: a case report and literature review.克罗恩病与系统性红斑狼疮并存:一例病例报告及文献综述
Eur J Gastroenterol Hepatol. 2020 Sep;32(9):1256-1262. doi: 10.1097/MEG.0000000000001775.
Orphanet J Rare Dis. 2013 May 3;8:67. doi: 10.1186/1750-1172-8-67.
4
Marked colonic wall thickening in lupus enteritis.狼疮性肠炎中显著的结肠壁增厚。
Intern Med. 2012;51(11):1451. doi: 10.2169/internalmedicine.51.7585. Epub 2012 Jun 1.
5
Inflammatory bowel disease and lupus: a systematic review of the literature.炎症性肠病与狼疮:文献系统综述。
J Crohns Colitis. 2012 Aug;6(7):735-42. doi: 10.1016/j.crohns.2012.03.005. Epub 2012 Apr 14.
6
The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis.第二届欧洲克罗恩病诊断与管理循证共识:定义与诊断
J Crohns Colitis. 2010 Feb;4(1):7-27. doi: 10.1016/j.crohns.2009.12.003. Epub 2010 Jan 15.
7
Gastrointestinal involvement in systemic lupus erythematosus: insight into pathogenesis, diagnosis and treatment.系统性红斑狼疮的胃肠道受累:发病机制、诊断和治疗的新见解。
World J Gastroenterol. 2010 Jun 28;16(24):2971-7. doi: 10.3748/wjg.v16.i24.2971.
8
CT findings and clinical activity in Crohn's disease.克罗恩病的CT表现与临床活动情况
Clin Imaging. 2009 Mar-Apr;33(2):123-9. doi: 10.1016/j.clinimag.2008.08.021.
9
Pulse steroids: how much is enough?脉冲式使用类固醇:多少剂量才足够?
Autoimmun Rev. 2006 Feb;5(2):111-3. doi: 10.1016/j.autrev.2005.08.003. Epub 2005 Aug 29.
10
[A case of elderly man with systemic lupus erythematosus (SLE) associated with paralytic ileus and fistula formation].[一例老年男性系统性红斑狼疮(SLE)合并麻痹性肠梗阻及瘘管形成的病例]
Nihon Shokakibyo Gakkai Zasshi. 1999 Apr;96(4):413-7.