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输尿管支架与经皮肾造瘘术治疗急性输尿管梗阻的比较 - 临床结果和生活质量:一项双中心前瞻性研究。

Ureteric stent versus percutaneous nephrostomy for acute ureteral obstruction - clinical outcome and quality of life: a bi-center prospective study.

机构信息

Urology Department, Rabin Medical Center, Hasharon Hospital, 7 Keren Kayemet St, 49372, Petah Tikva, Israel.

Sackler School of medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

BMC Urol. 2019 Aug 28;19(1):79. doi: 10.1186/s12894-019-0510-4.

Abstract

BACKGROUND

To compare quality of life (QoL) indices between ureteral stent (DJS) and nephrostomy tube (PCN) inserted in the setting of acute ureteral obstruction.

METHODS

Prospective bi-centered study. Over the span of 2 years, 45 DJS and 30 PCN patients were recruited. Quality of life was assessed by 2 questionnaires, EuroQol EQ-5D and 'Tube symptoms' questionnaire, at 2 time points (at discharge after drainage and before definitive treatment).

RESULTS

Patients' demographics and pre-drainage data were similar. There were no clinically significant differences in patient's recovery between the groups, including post procedural pain, defeverence, returning to baseline renal function, and septic shock complications. More DJS patients presented to the emergency room with complaints related to their procedure compared to PCN patients. At first, DJS patients complained more of urinary discomfort while PCN patients had worse symptoms relating to mobility and personal hygiene, with both groups achieving similar overall QoL score. At second time point, PCN patients' symptoms ameliorated while symptoms in the DJS group remained similar, translating to higher overall QoL score in the PCN group.

CONCLUSIONS

The two techniques had a distinct and significantly different impact on quality of life. Over time, PCN patients' symptoms relieve and their QoL improve, while DJS patients' symptoms persist. Specific tube related symptoms, and their dynamics over time, should be a major determinant in choosing the appropriate drainage method, especially when definitive treatment is not imminent.

摘要

背景

比较在急性输尿管梗阻的情况下置入输尿管支架(DJS)和肾造瘘管(PCN)的生活质量(QoL)指标。

方法

前瞻性双中心研究。在 2 年的时间内,招募了 45 名 DJS 和 30 名 PCN 患者。通过 2 个问卷,即 EuroQol EQ-5D 和“管症状”问卷,在 2 个时间点(引流后出院和明确治疗前)评估生活质量。

结果

患者的人口统计学和引流前数据相似。两组患者的恢复情况没有明显的临床差异,包括术后疼痛、退热、恢复基础肾功能和脓毒性休克并发症。与 PCN 患者相比,更多的 DJS 患者因与手术相关的投诉到急诊室就诊。最初,DJS 患者抱怨更多的是尿不适,而 PCN 患者的移动和个人卫生方面的症状更差,两组的总体 QoL 评分相似。在第二个时间点,PCN 患者的症状得到改善,而 DJS 组的症状保持相似,导致 PCN 组的总体 QoL 评分更高。

结论

这两种技术对生活质量有明显而显著的不同影响。随着时间的推移,PCN 患者的症状缓解,生活质量提高,而 DJS 患者的症状持续存在。特定的管相关症状及其随时间的动态变化,应该是选择适当引流方法的主要决定因素,尤其是在明确治疗不迫在眉睫的情况下。

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