Department of Radiology, Changhai Hospital of Shanghai, The Second Military Medical University, No.168 Changhai Road, Shanghai, 200433, China.
Department of Urology, Changhai Hospital of Shanghai, The Second Military Medical University, No.168 Changhai Road, Shanghai, 200433, China.
Cancer Imaging. 2019 Aug 27;19(1):59. doi: 10.1186/s40644-019-0245-1.
To evaluate whether readout-segment echo-planar imaging (RS-EPI) can provide better image quality in assessing bladder cancer than single-shot echo-planar imaging (SS-EPI) and to compare quantitative imaging parameters derived from both techniques.
Seventy patients with bladder lesions were enrolled and underwent diffusion-weighted imaging on a 3 Tesla magnetic resonance scanner using axial RS-EPI and SS-EPI techniques. Two observers independently assessed the susceptibility, detectability, motion artefacts and blurring of the images using qualitative scores. The signal-to-noise ratio (SNR), signal intensity ratio (SIR), contrast-to-noise ratio (CNR) and ADC values of the bladder lesions were measured and compared between the two techniques and between two observers. Qualitative and quantitative comparisons of image quality were performed using the Wilcoxon signed-rank test and paired t-test. In addition, the agreement of the ADC measurements was evaluated using ICC values and Bland-Altman plots.
Sixty-eight patients were included in the final analysis. The scores of image susceptibility, detectability and blurring for RS-EPI were significantly higher than those for SS-EPI (all p < 0.05), while the motion artefact was not. There were significant differences between RS-EPI and SS-EPI in the CNR and SIR values (all p < 0.05) but not in the SNR or ADC values (all p > 0.05). The ICC values and Bland-Altman plots also showed excellent agreement between the measured ADC values of the bladder lesions.
The RS-EPI technique provides significantly better image quality in patients with bladder cancer than the SS-EPI technique, without a significant difference in the ADC value.
评估读片回波平面成像（RS-EPI）在评估膀胱癌方面是否比单次激发回波平面成像（SS-EPI）提供更好的图像质量，并比较两种技术得出的定量成像参数。
70 例膀胱病变患者在 3T 磁共振扫描仪上进行扩散加权成像，采用轴位 RS-EPI 和 SS-EPI 技术。两位观察者分别使用定性评分独立评估图像的易感性、可检测性、运动伪影和模糊度。测量并比较两种技术和两位观察者之间膀胱病变的信噪比（SNR）、信号强度比（SIR）、对比噪声比（CNR）和 ADC 值。使用 Wilcoxon 符号秩检验和配对 t 检验对图像质量的定性和定量比较进行分析。此外，还使用 ICC 值和 Bland-Altman 图评估 ADC 测量的一致性。
最终有 68 例患者纳入分析。RS-EPI 的图像易感性、可检测性和模糊评分均显著高于 SS-EPI（均 p<0.05），而运动伪影则不然。RS-EPI 和 SS-EPI 之间在 CNR 和 SIR 值方面存在显著差异（均 p<0.05），但 SNR 或 ADC 值方面无显著差异（均 p>0.05）。ICC 值和 Bland-Altman 图也显示了膀胱病变 ADC 值测量之间的极好一致性。
与 SS-EPI 技术相比，RS-EPI 技术在膀胱癌患者中提供了显著更好的图像质量，而 ADC 值无显著差异。
