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上肢糖尿病性肌坏死:一种罕见并发症的非典型表现

Upper-Limb Diabetic Myonecrosis: Atypical Presentation of a Rare Complication.

作者信息

Jalali Zahra, Sharif Sakineh Khatoun

机构信息

Faculty of Medicine, Tabriz University of Medical Sciences, Imam Reza Hospital, Tabriz, Iran.

Rheumatology Research Center, Tabriz University for Medical Sciences, Tabriz, Iran.

出版信息

Am J Case Rep. 2019 Aug 28;20:1268-1272. doi: 10.12659/AJCR.917030.

Abstract

BACKGROUND Myonecrosis is an uncommon complication of poorly controlled diabetes, predominantly involving the lower limbs. It is an atypical presentation in the upper limbs. Here, we report a rare case with atypical involvement of the upper limbs. CASE REPORT A 53-year-old diabetic woman presented with left arm pain for the past week. She was not compliant with her medications. The patient denied any history of trauma or injection. Physical examination revealed a warm, tender, and erythematous swelling on the medial side of the left arm and was otherwise unremarkable. Her glycemic control was poor, with Hb A1C of 9.6%. Duplex ultrasonography demonstrated no evidence of fluid collection or thrombosis. An initial MRI (without contrast) report was misleadingly suggestive of polymyositis. Orthopedic consultant urged the patient to transfer to the operating room for aspiration of a probable infectious nidus, which resulted in a dry tap. Despite confusing radiological clues, ischemic myonecrosis was suspected, and second MRI studies (with contrast) reported necrosis. Tissue biopsy (the criterion standard) was withheld to avoid the risk of delayed healing or superimposed infection. Meanwhile, the patient received supportive treatment and achieved full recovery within 1 month. CONCLUSIONS Diabetic myonecrosis should be suspected in any poorly controlled diabetic patient presenting with otherwise unexplained muscle pain without any evidence of infection. Diagnosis can be made by MRI, leaving very few indications for invasive procedures. Analgesics and glycemic control are the mainstays of treatment.

摘要

背景

肌坏死是糖尿病控制不佳时罕见的并发症,主要累及下肢。上肢受累较为少见。在此,我们报告1例上肢出现非典型受累的罕见病例。病例报告:一名53岁的糖尿病女性,过去一周出现左臂疼痛。她未规律服药。患者否认有任何外伤或注射史。体格检查发现左臂内侧有温热、压痛且红斑性肿胀,其他方面无异常。她的血糖控制不佳,糖化血红蛋白为9.6%。双功超声检查未发现有积液或血栓形成的迹象。最初的MRI(无造影剂)报告错误地提示为多发性肌炎。骨科会诊医生敦促患者转至手术室,对可能的感染灶进行穿刺抽吸,结果抽得为空。尽管影像学线索令人困惑,但仍怀疑为缺血性肌坏死,第二次MRI检查(有造影剂)报告有坏死。为避免延迟愈合或叠加感染的风险,未进行组织活检(标准诊断方法)。同时,患者接受了支持性治疗,并在1个月内完全康复。结论:对于任何血糖控制不佳且出现无法解释的肌肉疼痛而无感染迹象的糖尿病患者,应怀疑糖尿病性肌坏死。可通过MRI进行诊断,很少有进行侵入性检查的指征。止痛和控制血糖是主要的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1d6/6753662/57bab0558adf/amjcaserep-20-1268-g001.jpg

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