Mariko Rinang, Darwin Eryati, Yanwirasti Yanwirasti, Hadinegoro Sri Rezeki
Postgraduate Biomedical Science, Faculty of Medicine, Andalas University, Padang, Indonesia.
Department of Pediatrics, Faculty of Medicine, Andalas University, General Hospital of Dr M. Djamil, Padang, Indonesia.
Open Access Maced J Med Sci. 2019 Jul 13;7(13):2119-2122. doi: 10.3889/oamjms.2019.569. eCollection 2019 Jul 15.
Dengue infection is one of the problems in the national health sector in Indonesia because the incidence and mortality in Indonesia due to dengue infection is still very high. In 2005 Indonesia became the highest contributor to dengue infection in Southeast Asia (53%) with 95.270 people and 1.298 deaths.
This study aims to analyse differences in angiopoietin-2 levels in dengue hemorrhagic fever (DHF) with and without shock.
This study was a consecutive sampling design with the research subject was obtained based on the order of admission to the hospital - the serum Angiopoietin-2 levels using the ELISA method. The statistical test used is the independent t-test. The value of p < 0.05 was said to be statistically significant.
The result showed that the mean of Angiopoietin-2 levels in DHF patients with shock was higher than in DHF (p < 0.05).
This study concluded that there was a difference in the average level of Angiopoietin-2 among DHF patients with shock compared to without shock.
登革热感染是印度尼西亚国家卫生部门面临的问题之一，因为印度尼西亚因登革热感染导致的发病率和死亡率仍然很高。2005年，印度尼西亚成为东南亚登革热感染的最大贡献国（53%），有95270人感染，1298人死亡。
本研究旨在分析有休克和无休克的登革出血热（DHF）患者血管生成素-2水平的差异。
本研究采用连续抽样设计，根据患者入院顺序确定研究对象，采用ELISA法检测血清血管生成素-2水平。使用的统计检验是独立t检验。p < 0.05的值被认为具有统计学意义。
结果显示，有休克的DHF患者血管生成素-2水平的平均值高于无休克的DHF患者（p < 0.05）。
本研究得出结论，有休克的DHF患者与无休克的DHF患者相比，血管生成素-2的平均水平存在差异。
