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良性淋巴上皮囊肿:两名免疫功能正常患者腮腺肿大的罕见原因。

Benign Lymphoepithelial Cyst: An Unusual Cause of Parotid Swelling in Two Immunocompetent Patients.

作者信息

Thong How Kit, Athar Primuharsa Putra Sabir Husin, Mustaffa Wan Muhaizan Wan

机构信息

KPJ Healthcare University College, Nilai, Negeri Sembilan, Malaysia.

Ear, Nose & Throat-Head & Neck Consultant Clinic, KPJ Seremban Specialist Hospital, Negeri Sembilan, Malaysia.

出版信息

Open Access Maced J Med Sci. 2019 Jul 14;7(13):2142-2145. doi: 10.3889/oamjms.2019.577. eCollection 2019 Jul 15.

DOI:10.3889/oamjms.2019.577
PMID:31456841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6698116/
Abstract

BACKGROUND

Lymphoepithelial cysts, which are benign and slow-growing tumours, usually involve the head and neck regions. Benign lymphoepithelial cysts (BLECs) are the most common cause of parotid swelling in human immunodeficiency virus (HIV)-positive patients and are less common in immunocompetent patients.

CASE PRESENTATION

Here, we present two cases of immunocompetent patients with long-standing, progressively enlarging parotid swelling. Postoperative histopathological examination of these patients revealed features of BLEC.

CONCLUSION

Wide surgical excision is the gold standard for treatment and recurrences is rare. These cases are of particular interest because of the rarity of BLEC in HIV-negative patients and highlight an important differential diagnosis of parotid swelling.

摘要

背景

淋巴上皮囊肿是一种良性且生长缓慢的肿瘤,通常累及头颈部区域。良性淋巴上皮囊肿(BLECs)是人类免疫缺陷病毒(HIV)阳性患者腮腺肿大最常见的原因,在免疫功能正常的患者中较少见。

病例报告

在此,我们报告两例免疫功能正常的患者,他们长期存在腮腺肿大且逐渐增大。对这些患者进行术后组织病理学检查发现了良性淋巴上皮囊肿的特征。

结论

广泛手术切除是治疗的金标准,复发罕见。这些病例特别值得关注,因为良性淋巴上皮囊肿在HIV阴性患者中罕见,并突出了腮腺肿大的重要鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/d21c158299a0/OAMJMS-7-2142-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/a8693a65deb5/OAMJMS-7-2142-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/7b9ecdb5774e/OAMJMS-7-2142-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/3c4880e61335/OAMJMS-7-2142-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/2978b41a1742/OAMJMS-7-2142-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/d21c158299a0/OAMJMS-7-2142-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/a8693a65deb5/OAMJMS-7-2142-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/7b9ecdb5774e/OAMJMS-7-2142-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/3c4880e61335/OAMJMS-7-2142-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/2978b41a1742/OAMJMS-7-2142-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e12/6698116/d21c158299a0/OAMJMS-7-2142-g005.jpg

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本文引用的文献

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Case Rep Otolaryngol. 2017;2017:5169364. doi: 10.1155/2017/5169364. Epub 2017 Jul 30.
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Lymphoepithelial cyst of the submandibular gland.下颌下腺淋巴上皮囊肿
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