State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Department of Horticulture, Zhejiang University, Hangzhou 310058, Zhejiang, China.
Sci Adv. 2019 Aug 21;5(8):eaav9801. doi: 10.1126/sciadv.aav9801. eCollection 2019 Aug.
A parasite-infected host may promote performance of associated insect vectors; but possible parasite effects on nonvector insects have been largely unexplored. Here, we show that , the largest genus of plant viruses and transmitted exclusively by whitefly, reprogram plant immunity to promote the fitness of the vector and suppress performance of nonvector insects (i.e., cotton bollworm and aphid). Infected plants accumulated begomoviral βC1 proteins in the phloem where they were bound to the plant transcription factor WRKY20. This viral hijacking of WRKY20 spatiotemporally redeployed plant chemical immunity within the leaf and had the asymmetrical benefiting effects on the begomoviruses and its whitefly vectors while negatively affecting two nonvector competitors. This type of interaction between a parasite and two types of herbivores, i.e., vectors and nonvectors, occurs widely in various natural and agricultural ecosystems; thus, our results have broad implications for the ecological significance of parasite-vector-host tripartite interactions.
被寄生虫感染的宿主可能会促进相关昆虫媒介的表现；但寄生虫对非媒介昆虫的可能影响在很大程度上尚未得到探索。在这里，我们表明，作为最大的植物病毒属，仅通过粉虱传播，重新编程植物免疫以促进媒介的适应性，并抑制非媒介昆虫（即棉铃虫和蚜虫）的表现。受感染的植物在韧皮部积累了双生病毒 βC1 蛋白，在那里它们与植物转录因子 WRKY20 结合。这种病毒劫持 WRKY20 时空重新部署了叶片内的植物化学免疫，对双生病毒及其粉虱媒介具有不对称的有益影响，同时对两种非媒介竞争者产生负面影响。这种寄生虫和两种类型的草食动物（即媒介和非媒介）之间的相互作用在各种自然和农业生态系统中广泛发生；因此，我们的研究结果对寄生虫-媒介-宿主三方相互作用的生态意义具有广泛的影响。
