Sourial N, Fenton F
McGill University, Montreal, Quebec.
Can J Psychiatry. 1988 Dec;33(9):846-50. doi: 10.1177/070674378803300912.
A hypogonadal male with 48 XXYY Karyotype--a rare Klinefelter's syndrome variant--is presented with review of the literature. Cautious initiation of testosterone replacement therapy to our patient was associated with sexual maturation and, interestingly enough, disappearance of his longstanding aggressive fantasies and behaviors towards females. An explanatory hypothesis is proposed and clues for early detection of the syndrome are suggested.
本文报告了一例核型为48 XXYY的性腺功能减退男性——一种罕见的克兰费尔特综合征变体，并对相关文献进行了综述。谨慎地对我们的患者开始睾酮替代治疗，与性成熟相关，有趣的是，他长期以来对女性的攻击性幻想和行为也消失了。本文提出了一个解释性假说，并给出了该综合征早期检测的线索。
