Fritsch G, Ebner F, Schneider G
Department of Pediatrics, University of Graz, Austria.
Eur Neurol. 1988;28(6):306-10. doi: 10.1159/000116291.
The CT investigations of 156 children with partial epilepsies are analyzed. Pathological findings appeared in 39%, particularly atrophic changes and porencephalic lesions. According to the seizure type their incidence was higher in children who had secondary generalized seizures (46%) than in children with isolated partial seizures (30%) or complex partial seizures with or without secondary generalization (16%). Furthermore, pathological findings occurred more frequently in children with perinatal etiology (37%) than in familial (26%) or idiopathic cases (10%). A symptomatic epilepsy due to a cerebral tumor or a vascular lesion was found in 10%. There was a high correlation between neurodevelopmental disturbances and abnormal CT findings, however also 17 neurological normal children had pathological CT findings.
对156例部分性癫痫患儿的CT检查结果进行了分析。39%出现了病理改变,尤其是萎缩性改变和脑穿通畸形病变。根据癫痫发作类型,继发性全面性发作患儿的发病率(46%)高于单纯部分性发作患儿(30%)或伴有或不伴有继发性全面性发作的复杂部分性发作患儿(16%)。此外,围产期病因患儿的病理改变发生率(37%)高于家族性(26%)或特发性病例(10%)。10%的患儿因脑肿瘤或血管病变导致症状性癫痫。神经发育障碍与CT异常表现之间存在高度相关性,然而,17例神经系统正常的儿童也有CT病理表现。