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部分运动性癫痫的头颅计算机断层扫描

Cranial computed tomography in partial motor seizures.

作者信息

Hussain Jageer, Srinivasan S, Serane V Tiroumourougane, Mahadevan S, Elangovan S, Bhuvaneswari V

机构信息

Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.

出版信息

Indian J Pediatr. 2004 Jul;71(7):641-4. doi: 10.1007/BF02724126.

Abstract

OBJECTIVE

To identify the pattern of intracranial structural lesions in developmentally normal children with partial motor seizures by computed tomography and to monitor the behavior of single ring enhancing lesion (SREL) after a period of time with or without treatment.

METHODS

Consecutive developmentally normal children between one year and twelve years with partial motor seizures in a tertiary care referral Hospital. After clinical examination and appropriate investigation for tuberculosis and cysticercosis, CT scan was performed. In addition to anticonvulsants, children received antituberculous or anticysticercal therapy if indicated. Repeat CT was performed on children with SREL after 6 months.

RESULTS

Computed tomography was abnormal in 102 (68%) children. Majority of the children (75) had SREL. The lesions were located in decreasing order of frequency in the parietal lobe (65), frontal lobe (7), occipital lobe (1), temporal lobe (1) and cerebellum (1). Repeat CT scan was performed on 50 of the 75 children with SREL. Among these, in 41 children who were only on antiepileptic therapy, the SREL had decreased in size in thirty-two whereas in the rest (9), there was no change in the size.

CONCLUSION

Awareness of the existence of disappearing SREL lesions is essential to avoid unnecessary treatment with antituberculous or anticysticercal therapy and provides ample justification in treating with anticonvulsant drugs only.

摘要

目的

通过计算机断层扫描确定部分性运动性癫痫发作的发育正常儿童的颅内结构病变模式,并观察单个环形强化病变(SREL)在一段时间内无论治疗与否的变化情况。

方法

在一家三级转诊医院中,对年龄在1岁至12岁之间、患有部分性运动性癫痫发作的发育正常儿童进行连续观察。在进行临床检查并对结核病和囊尾蚴病进行适当检查后,进行CT扫描。除抗惊厥药物外,如有指征,儿童还接受抗结核或抗囊尾蚴治疗。对患有SREL的儿童在6个月后进行重复CT检查。

结果

102名(68%)儿童的计算机断层扫描结果异常。大多数儿童(75名)有SREL。病变按频率递减顺序位于顶叶(65例)、额叶(7例)、枕叶(1例)、颞叶(1例)和小脑(1例)。对75名患有SREL的儿童中的50名进行了重复CT扫描。其中,在仅接受抗癫痫治疗的41名儿童中,32名儿童的SREL大小减小,其余9名儿童的SREL大小无变化。

结论

认识到SREL病变会消失这一点对于避免不必要的抗结核或抗囊尾蚴治疗至关重要,并且为仅使用抗惊厥药物治疗提供了充分的依据。

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