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锌和乙二胺四乙酸对兔和豚鼠不同平滑肌组织中镉含量的影响。

Effects of zinc and EDTA on tissue cadmium in various smooth muscles in rabbit and guinea-pig.

作者信息

Ueda F, Nagata M, Nagata T, Shimazaki Y

机构信息

Department of Veterinary Public Health, Nippon Veterinary and Zootechnical College, Tokyo, Japan.

出版信息

Gen Pharmacol. 1988;19(5):661-4. doi: 10.1016/0306-3623(88)90124-3.

DOI:10.1016/0306-3623(88)90124-3
PMID:3145900
Abstract
  1. The effects of zinc (Zn2+) and ethylenediaminetetra-acetic acid (EDTA) on tissue cadmium (Cd2+) were investigated in the smooth muscles of rabbit trachea, taenia coli, aorta and guinea-pig taenia coli. 2. After an Cd uptake in high-K2+ solution, samples were rinsed with cold high-K2+, cold Zn2+ or cold EDTA solution without Cd2+ and the results were quantitatively different from each other. 3. Concentration-response curves were obtained with each treatment of cold solution. 4. It is suggested that tissue Cd2+ can be divided into 3 fractions in the surface membrane and there is another fraction in cellular space.
摘要
  1. 在兔气管、结肠带、主动脉平滑肌以及豚鼠结肠带中研究了锌(Zn2+)和乙二胺四乙酸(EDTA)对组织镉(Cd2+)的影响。2. 在高钾溶液中摄取镉后,将样本用不含Cd2+的冷高钾溶液、冷Zn2+溶液或冷EDTA溶液冲洗,结果彼此在数量上有所不同。3. 对每种冷溶液处理都获得了浓度-反应曲线。4. 提示组织Cd2+在表面膜中可分为3个部分,在细胞间隙中还有另一部分。

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