Koufman J A, Branch M E, Ryu J H
Department of Surgery, Bowman Gray School of Medicine, Wake Forest University Medical Center, Winston-Salem, North Carolina 27103.
J Otolaryngol. 1988 Aug;17(5):223-6.
In a previously defined canine model of subglottic stenosis, two different wavelength lasers--the carbon dioxide (CO2) and the neodymium-yttrium aluminum garnet (Nd:YAG)--were used as the principal surgical therapy, and the results were compared. Two lathyrogenic agents, colchicine and penicillamine, were also used in a subset of each treatment group in order to determine their effect as an adjunct to laser therapy in the treatment of subglottic stenosis. The CO2 laser treatment group showed an overall improvement; the Nd:YAG laser treatment group showed a worsening of subglottic stenosis. The dogs treated with the lathyrogenic agents had no added benefit from the use of these agents.
在先前定义的犬声门下狭窄模型中，两种不同波长的激光——二氧化碳（CO2）激光和钕钇铝石榴石（Nd:YAG）激光——被用作主要手术治疗方法，并对结果进行了比较。在每个治疗组的一个亚组中还使用了两种致纤维化剂，秋水仙碱和青霉胺，以确定它们作为激光治疗声门下狭窄辅助药物的效果。CO2激光治疗组总体有所改善；Nd:YAG激光治疗组声门下狭窄情况恶化。使用致纤维化剂治疗的犬只并未从这些药物的使用中获得额外益处。
