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改性1,2,4-三唑衍生物的合成、化合物、乳化及抗菌活性

Synthesis, Compound, Emulsification, and Antibacterial Activity of Modified 1,2,4-Trizaole Derivatives.

作者信息

Guo Haoquan, Dong Yuguo, Zhu Shuai, Que Han, Lu Xinyu, Zhu Xiaojun, Cheng Kanghua, Gu Xiaoli

机构信息

College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.

出版信息

ACS Omega. 2019 Jun 3;4(6):9680-9685. doi: 10.1021/acsomega.9b00691. eCollection 2019 Jun 30.

DOI:10.1021/acsomega.9b00691
PMID:31460058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6648659/
Abstract

Three modified 1,2,4-trizaole derivatives were synthesized and compounded in pairs. Their structures were confirmed by H NMR and ESI-MS. Antibacterial tests were proceeded to evaluate the fungicidal activity of synthesized compounds. The results of antibacterial tests showed that the synthesized compounds exhibited good antibacterial activities against , , and at a ratio of 5:5. In order to improve the water solubility of target products, emulsification experiments were carried out and beta-cypermethrin was added as a pesticide. The appropriate emulsifier types and dosage ratios for the synthesized compounds were finally screened out.

摘要

合成了三种改性1,2,4 - 三唑衍生物并进行两两复配。通过氢核磁共振(H NMR)和电喷雾电离质谱(ESI - MS)对其结构进行了确证。进行了抗菌测试以评估合成化合物的杀菌活性。抗菌测试结果表明,合成化合物在5:5的比例下对[此处原文未提及具体菌种]表现出良好的抗菌活性。为了提高目标产物的水溶性,进行了乳化实验,并添加了高效氯氰菊酯作为农药。最终筛选出了合成化合物合适的乳化剂类型和用量比例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83fb/6648659/2ca8d0336285/ao-2019-006919_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83fb/6648659/2ca8d0336285/ao-2019-006919_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83fb/6648659/2ca8d0336285/ao-2019-006919_0001.jpg

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