Torres Orlando Jorge M, Rezende Marcelo Bruno de, Waechter Fábio Luiz, Neiva Romerito Fonseca, Moraes-Junior José Maria A, Torres Camila Cristina S, Fernandes Eduardo de Souza M
Department of Gastrointestinal Surgery, Hepatopancreatobiliary Unit, Universidade Federal do Maranhão, São Luiz, MA.
Department of Gastrointestinal and Transplant Surgery, Hospital Israelita Albert Einstein, São Paulo, SP.
Arq Bras Cir Dig. 2019 Aug 26;32(2):e1442. doi: 10.1590/0102-672020190001e1442.
Solid pseudopapillary tumor of the pancreas is a rare low-grade malignant neoplasm. Most patients present with nonspecific symptoms until the tumor becomes large. Complete surgical resection by pancreatoduodenectomy is the treatment of choice for tumors located in the head of the pancreas.
To analyzed the clinicopathologic features, management, and outcomes of patients who had solid pseudopapillary tumor of the head pancreas and underwent surgical resection.
Were analyzed 16 patients who underwent pancreatoduodenectomy for this condition.
Mean age was 25.7 years old, and 15 patients were female (93.7%). Nonspecific abdominal pain was present in 14 (87.5%). All underwent computed tomography and/or magnetic resonance imaging as part of diagnostic workup. The median diameter of the tumor was 6.28 cm, and surgical resection was performed with open or laparoscopic pancreatoduodenectomy without neoadjuvant chemotherapy. Postoperative complications occurred in six patients (37.5%) and included pancreatic fistula without mortality. The mean of hospital stay was 10.3 days. Median follow-up was 3.6 years, and no patient had local recurrence or metastatic disease.
For these patients surgical resection with pancreatoduodenectomy is the treatment of choice showing low morbidity, no mortality, and good long-term survival.
胰腺实性假乳头状瘤是一种罕见的低级别恶性肿瘤。大多数患者在肿瘤变大之前表现出非特异性症状。对于位于胰头的肿瘤，通过胰十二指肠切除术进行完整的手术切除是首选治疗方法。
分析患有胰头实性假乳头状瘤并接受手术切除的患者的临床病理特征、治疗方法及预后。
分析16例因该疾病接受胰十二指肠切除术的患者。
平均年龄为25.7岁，15例为女性（93.7%）。14例（87.5%）出现非特异性腹痛。作为诊断检查的一部分，所有患者均接受了计算机断层扫描和/或磁共振成像检查。肿瘤的中位直径为6.28厘米，手术切除采用开放或腹腔镜胰十二指肠切除术，未进行新辅助化疗。6例患者（37.5%）发生术后并发症，包括胰瘘，无死亡病例。平均住院时间为10.3天。中位随访时间为3.6年，无患者出现局部复发或转移性疾病。
对于这些患者，胰十二指肠切除术是首选治疗方法，具有低发病率、无死亡率和良好的长期生存率。
