Vorotyntseva N V, Reĭzis A R, Drondina A N, Vasil'eva V I, Asratian A A
Zh Mikrobiol Epidemiol Immunobiol. 1988 Nov(11):31-5.
During a year an overall serological examination of 1,200 children hospitalized with the diagnosis of viral hepatitis was carried out with a view to establish the presence of hepatitis A and hepatitis B markers (anti-HAV IgM, HBsAg, anti-HBs, anti-HBc and anti-HBe IgM) by means of the enzyme immunoassay and radioimmunoassay. The average annual proportion of cases of hepatitis A (61.4%), hepatitis B (20.4%), hepatitis non A, non B (11.2%) and mixed infection (7.0%) among children, as well as seasonal and age-group fluctuations of this proportion, were established. The etiological structure of viral hepatitides, based on commonly accepted clinico-epidemiological diagnostic criteria, was shown to differ from their true etiological structure as determined in accordance with specific serological markers detected in this investigation.
在一年的时间里，对1200名被诊断为病毒性肝炎而住院的儿童进行了全面的血清学检查，目的是通过酶免疫测定法和放射免疫测定法确定甲型肝炎和乙型肝炎标志物（抗甲型肝炎病毒IgM、乙肝表面抗原、抗乙肝表面抗体、抗乙肝核心抗体和抗乙肝e抗体IgM）的存在情况。确定了儿童中甲型肝炎（61.4%）、乙型肝炎（20.4%）、非甲非乙型肝炎（11.2%）和混合感染（7.0%）病例的年平均比例，以及该比例的季节性和年龄组波动情况。结果表明，基于普遍接受的临床流行病学诊断标准的病毒性肝炎病因结构，与根据本次调查中检测到的特定血清学标志物确定的真实病因结构不同。
