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[儿童甲型和乙型肝炎混合感染]

[Viral hepatitis A and B as a mixed infection in children].

作者信息

Reĭzis A R, Drondina A K, Asratian A A, Mardanly S G, Rybalkina T N

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1988 Nov(11):27-30.

PMID:3218422
Abstract

Serological examinations of 1,200 children, hospitalized at the viral hepatitis department over a year, for the presence of hepatitis A (HA) and hepatitis B (HB) markers have revealed a 7% incidence rate of mixed HA and HB infections. Three variants of mixed infection have been established (true mixed infection, HA combined with asymptomatic HBsAg carriership, cross superinfection) and the relative significance of each of them has been determined. Mixed infection took an unfavorable course with a tendency to the prolongation of the pathological process eventuating in chronic hepatitis, especially in cases of true mixed infections (15.9%).

摘要

对一年来在病毒性肝炎科室住院的1200名儿童进行的血清学检查,以检测甲型肝炎(HA)和乙型肝炎(HB)标志物的存在情况,结果显示HA和HB混合感染的发生率为7%。已确定了三种混合感染变体(真正的混合感染、HA合并无症状HBsAg携带者、交叉重叠感染),并确定了每种变体的相对重要性。混合感染病程不利,病理过程有延长的趋势,最终导致慢性肝炎,尤其是在真正的混合感染病例中(15.9%)。

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