Suresh Varun, Yaddanapudi Lakshmi Narayana, Podder Subrata
Department of Anaesthesia and Intensive Care, PGIMER, Chandigarh, India.
Indian J Anaesth. 2019 Aug;63(8):640-647. doi: 10.4103/ija.IJA_377_19.
Glasgow Coma scale (GCS), the most widely used tool for evaluation of the level of consciousness has various limitations. The Full Outline of UnResponsiveness (FOUR) score is a possible alternative. The present study was designed to examine the inter-rater reliability and outcome predictability of these scores in the Intensive Care Unit (ICU).
The GCS and FOUR scores of 111 adult patients with altered sensorium, admitted to the ICU, were assessed as early as possible after admission by the Senior Resident (SR), Junior Resident (JR) and Staff Nurse (SN) of ICU. The outcomes measured survival and modified Rankin Scale (mRS) and Glasgow outcome scale (GOS) of the patients at discharge.
The inter-observer agreement was measured using the kappa ('') statistic. For GCS it was higher ( = 0.472 to 0.555) than FOUR score ( = 0.352 to 0.448). A higher '' score in either score was recorded between SR and JR. Linear regression analysis showed no significant association of either score with the duration of ICU stay or mechanical ventilation. Survival in ICU was correlated with both GCS and FOUR scores on logistic regression. GOS and mRS were correlated with either GCS or FOUR scores on ordinal regression.
The inter-observer agreement with FOUR score was not superior to GCS in this study, possibly due to lack of familiarity with the FOUR score. Both the scores were statistically correlated with the rate of survival.
格拉斯哥昏迷量表(GCS)是评估意识水平最广泛使用的工具,但存在各种局限性。全面无反应性量表(FOUR)评分可能是一种替代方法。本研究旨在检验重症监护病房(ICU)中这些评分的评分者间信度和结果可预测性。
对111例入住ICU且意识改变的成年患者,在入院后尽早由ICU的高级住院医师(SR)、初级住院医师(JR)和护士(SN)评估其GCS和FOUR评分。测量患者出院时的生存情况、改良Rankin量表(mRS)和格拉斯哥预后量表(GOS)。
使用kappa(κ)统计量测量观察者间一致性。对于GCS,其一致性较高(κ = 0.472至0.555),高于FOUR评分(κ = 0.352至0.448)。SR和JR之间在任一评分中记录的κ评分更高。线性回归分析显示,两种评分与ICU住院时间或机械通气时间均无显著相关性。在逻辑回归中,ICU中的生存情况与GCS和FOUR评分均相关。在有序回归中,GOS和mRS与GCS或FOUR评分相关。
在本研究中,FOUR评分的观察者间一致性并不优于GCS,可能是由于对FOUR评分缺乏熟悉度。两种评分在统计学上均与生存率相关。