Brewster O, Clement N D, Duckworth A D, McQueen M M, Court-Brown C M
Royal United Hospitals Bath, Combe Park, Avon, BA13NG, UK.
Department of Orthopaedics and Trauma, The Royal Infirmary of Edinburgh, Little France, Edinburgh, EH16 4SA, UK.
Eur J Orthop Surg Traumatol. 2020 Jan;30(1):157-162. doi: 10.1007/s00590-019-02522-3. Epub 2019 Aug 29.
The aim of this study was to describe the mortality risk after calcaneal fractures which required internal fixation and evaluate predictors of survival. During the observed 11-year period (1995-2006), 178 consecutive patients underwent operative fixation for displaced intra-articular calcaneal fractures. Patient demographics, mechanism of injury, and social deprivation (Carstairs index) were recorded. Mortality was obtained from patient notes. Causes of mortality were obtained from the national database. Standardised mortality ratios (SMRs) were calculated. Ten patients were lost to follow-up. Of the remaining 168 patients, the mean age was 41 (range 14-77) years. Females [n = 33, 46.3 standard deviation (SD) 17.1 years] were significantly (difference 6.5 years, 95% CI 1.1-11.9, p = 0.02) older than male patients (n = 135, 39.8 SD 13.4 years). During the study period, 28 patients died. The overall unadjusted survival rate was 92.8% (95% CI 87.0-98.7) at 10 years and 81.9% (95% CI 76.2-87.6) at 15 years. The SMR at 10 years was 5.2 (95% CI 2.8-13.3) for males and 1.4 (95% CI - 4.9 to 7.8) for females. Cox regression analysis demonstrated male gender to be a significant predictor of mortality (hazard ratio 2.77, 95% 3.83-9.65, p = 0.01) adjusted for age and social deprivation. Male patients requiring internal fixation of intra-articular calcaneal fractures have a significantly increased mortality risk compared to an age- and gender-matched population. Further study is warranted to fully identify the reasons behind this, which may enable their survival to be improved.Level of evidence Retrospective Cohort study, Level 4.
本研究的目的是描述需要内固定的跟骨骨折后的死亡风险,并评估生存的预测因素。在观察的11年期间(1995 - 2006年),178例连续患者因移位的关节内跟骨骨折接受了手术固定。记录了患者的人口统计学资料、损伤机制和社会剥夺情况(卡斯尔斯指数)。死亡率从患者病历中获取。死亡原因从国家数据库中获取。计算了标准化死亡率(SMR)。10例患者失访。在其余168例患者中,平均年龄为41岁(范围14 - 77岁)。女性患者(n = 33,平均年龄46.3岁,标准差17.1岁)比男性患者(n = 135,平均年龄39.8岁,标准差13.4岁)显著年长(相差6.5岁,95%可信区间1.1 - 11.9,p = 0.02)。在研究期间,28例患者死亡。10年时总体未调整生存率为92.8%(95%可信区间87.0 - 98.7),15年时为81.9%(95%可信区间76.2 - 87.6)。男性10年时的SMR为5.2(95%可信区间2.8 - 13.3),女性为1.4(95%可信区间 - 4.9至7.8)。Cox回归分析表明,在调整年龄和社会剥夺因素后,男性是死亡的显著预测因素(风险比2.77,95% 3.83 - 9.65,p = 0.01)。与年龄和性别匹配的人群相比,需要对关节内跟骨骨折进行内固定的男性患者死亡风险显著增加。有必要进行进一步研究以充分确定其背后的原因,这可能有助于提高他们的生存率。证据水平:回顾性队列研究,4级。