Shedko E D, Tyumentseva M A
Central Research Institute of Epidemiology, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2019;119(7):95-102. doi: 10.17116/jnevro201911907195.
Multiple sclerosis (MS) is a chronic autoimmune disease affecting brain and spinal cord. Nowadays, MS diagnosis at early stages is difficult since the causes and mechanisms of the disease onset have not yet been fully discovered. The MS diagnosis is a complex process, and understanding molecular mechanisms of the disease as well as searching for biomarkers are principal directions in MS diagnosis. In this review, the authors present promising biomarkers for MS found in the cerebrospinal fluid.
多发性硬化症（MS）是一种影响大脑和脊髓的慢性自身免疫性疾病。如今，由于该疾病发病的原因和机制尚未完全明确，早期MS诊断较为困难。MS诊断是一个复杂的过程，了解该疾病的分子机制以及寻找生物标志物是MS诊断的主要方向。在这篇综述中，作者介绍了在脑脊液中发现的有前景的MS生物标志物。
