Department of Sociology, University of Alabama at Birmingham, HHB 460H, 1720 2nd Ave South, Birmingham, AL 35294-1152, USA.
UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, 312 Civitan International Research Center (CIRC 312), 1720 2nd Avenue South, Birmingham, AL 35294-0021, USA.
Epilepsy Behav. 2019 Oct;99:106480. doi: 10.1016/j.yebeh.2019.106480. Epub 2019 Aug 26.
This exploratory study examined the impact of health literacy on quality of life (QoL) in patients with treatment-resistant epilepsy (TRE). Health literacy is a discrete form of literacy in which an individual can readily interpret prose and apply that skill to understand medical, pharmaceutical, and self-management information. From the perspectives of cultural health capital (CHC) and social disability theory, we hypothesized that greater levels of health literacy would be associated with a higher QoL score. The sample (n = 79) included adult patients with TRE enrolled in the University of Alabama at Birmingham Cannabidiol Program. The data were analyzed by using nested linear regression. Respondents aged 19-63 years (mean, standard deviation [SD] = 32.9 [13.65]) and were 92% white; 44% of patients were in Special Education until age 21 years, and 29% reported a total annual family income of less than $25,000. Significant bivariate relationships were found between health literacy and QoL (p = .004), age (p = .0001), and income (p = .036). There was a significant difference in health literacy scores for patients who completed high school or less (mean [SD] = 0.68 [0.86]) and those with any postsecondary education (mean [SD] = 1.59 [1.0]). The regression results showed health literacy to be positively associated with QoL where a 1% increase in health literacy was associated with a 6.61-point increase in QoL (p = .004), and this pattern persisted through each addition of other independent factors and control variables. This is one of the first studies investigating the role of health literacy in QoL among patients with TRE. The results suggest that health literacy is important and may function as a tool through which healthcare participation is expanded. Further research is needed with larger, more diverse, and longitudinal samples to accurately model the development of health literacy and its impact on QoL in this population.
这项探索性研究考察了健康素养对治疗抵抗性癫痫（TRE）患者生活质量（QoL）的影响。健康素养是一种独立的读写能力形式，个体可以轻松地解释散文并应用该技能来理解医学、药学和自我管理信息。从文化健康资本（CHC）和社会残疾理论的角度来看，我们假设更高水平的健康素养与更高的 QoL 评分相关。该样本（n=79）包括参加阿拉巴马大学伯明翰分校大麻素计划的 TRE 成年患者。使用嵌套线性回归分析数据。受访者年龄为 19-63 岁（平均值，标准差[SD]=32.9[13.65]），92%为白人；44%的患者在 21 岁之前接受特殊教育，29%的患者报告家庭年收入低于 25000 美元。健康素养和 QoL（p=0.004）、年龄（p=0.0001）和收入（p=0.036）之间存在显著的双变量关系。高中及以下学历的患者健康素养得分（平均值[SD]=0.68[0.86]）和任何高等教育学历的患者健康素养得分（平均值[SD]=1.59[1.0]）之间存在显著差异。回归结果显示，健康素养与 QoL 呈正相关，健康素养增加 1%，QoL 增加 6.61 分（p=0.004），并且这种模式在加入其他独立因素和控制变量后仍然存在。这是首次研究健康素养在 TRE 患者 QoL 中的作用的研究之一。结果表明，健康素养很重要，并且可能作为一种工具，通过该工具可以扩大医疗保健的参与度。需要进一步开展研究，使用更大、更多样化和纵向的样本，以准确地对该人群的健康素养发展及其对 QoL 的影响进行建模。
