Graduate School of Nursing Science, University of Miyazaki, Miyazaki, Japan.
Department of Obstetrics and Gynaecology, University of Miyazaki, Miyazaki, Japan.
J Psychosom Obstet Gynaecol. 2020 Sep;41(3):240-245. doi: 10.1080/0167482X.2019.1658734. Epub 2019 Aug 30.
we aimed to estimate the anxiety levels of pregnant women following maternal serum screening for CMV infection. In this case-control study conducted from April 2016 to June 2017, we enrolled all pregnant women referred to our hospital who were CMV immunoglobulin (Ig) M antibody positive (IgM-positive group, = 51); further, those who were CMV IgG positive but IgM negative (IgM-negative group, = 51) during the same period were included as study controls. Data were collected on patient characteristics, CMV IgM levels, and whether patients were accompanied by their partners during the first hospital visit after CMV IgM testing. The State-Trait Anxiety Inventory was used to assess anxiety levels. Both groups were age matched [mean age (years): IgM-positive, 30 ± 4.2 and IgM-negative, 29.9 ± 4.6]. The mean state-anxiety score was higher in the IgM-positive group (53 ± 9.6) than in the IgM-negative group (38.5 ± 7.0, < .05) with no between-group differences in trait-anxiety scores. Similarly, a higher number of women were accompanied by their partners in the IgM-positive group. The state-anxiety scores and CMV IgM levels were not correlated in the IgM-positive group. Counseling support is essential for IgM-positive pregnant women following serum screening, and the screening should be avoided if support systems are unavailable.
我们旨在评估巨细胞病毒(CMV)感染母血清筛查后孕妇的焦虑水平。在这项 2016 年 4 月至 2017 年 6 月进行的病例对照研究中,我们纳入了所有因 CMV 免疫球蛋白(Ig)M 抗体阳性(IgM 阳性组,n=51)而转诊至我院的孕妇;此外,还纳入了同期 CMV IgG 阳性但 IgM 阴性(IgM 阴性组,n=51)的患者作为研究对照。收集了患者特征、CMV IgM 水平以及患者在 CMV IgM 检测后首次就诊时是否有伴侣陪同的信息。采用状态-特质焦虑量表评估焦虑水平。两组患者的年龄匹配[平均年龄(岁):IgM 阳性组 30±4.2,IgM 阴性组 29.9±4.6]。与 IgM 阴性组相比,IgM 阳性组的状态焦虑评分更高(53±9.6 vs. 38.5±7.0,<.05),特质焦虑评分无组间差异。同样,IgM 阳性组中有更多的女性有伴侣陪同。在 IgM 阳性组中,状态焦虑评分与 CMV IgM 水平之间无相关性。对于血清筛查后 IgM 阳性的孕妇,需要提供咨询支持,若支持系统不可用,则应避免进行筛查。