Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Department of Pharmacy Services, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Infect Control Hosp Epidemiol. 2019 Nov;40(11):1294-1296. doi: 10.1017/ice.2019.238. Epub 2019 Aug 30.
We implemented a guideline for appropriate acid suppressant use in hematology-oncology patients. This intervention resulted in a sustained reduction in proton pump inhibitor (PPI) use without an increase in rates of gastrointestinal bleeding. Practice guidelines are effective in reducing PPI use, which is associated with risk of Clostridioides difficile infection.
我们为血液肿瘤科患者实施了适当使用抑酸剂的指南。这一干预措施使得质子泵抑制剂(PPI)的使用持续减少,而胃肠道出血的发生率并未增加。实践指南在减少 PPI 使用方面是有效的,因为 PPI 使用与艰难梭菌感染的风险相关。