Division of Allergy/Immunology, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, 3950 Beaubien, 4th Floor, Pediatric Specialty Building, Detroit, MI 48201, USA.
Division of Hospital Medicine, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI, USA.
Pediatr Clin North Am. 2019 Oct;66(5):967-979. doi: 10.1016/j.pcl.2019.06.012. Epub 2019 Aug 5.
Inner-city children with asthma are known to have high disease mortality and morbidity. Frequently, asthma in this high-risk population is difficult to control and more severe in nature. Several factors, including socioeconomic hardship, ability to access to health care, adherence to medication, exposure to certain allergens, pollution, crowd environment, stress, and infections, play an important role in the pathophysiology of inner-city asthma. Comprehensive control of home allergens and exposure to tobacco smoke, the use of immune based therapies, and school-based asthma programs have shown promising results in asthma control in this population.
城市内哮喘儿童的疾病死亡率和发病率较高是众所周知的。通常,高风险人群中的哮喘难以控制,且性质更为严重。包括社会经济困难、获得医疗保健的能力、对药物的依从性、接触某些过敏原、污染、拥挤环境、压力和感染在内的多种因素在城市内哮喘的病理生理学中发挥着重要作用。全面控制家庭过敏原和接触烟草烟雾、使用基于免疫的疗法以及基于学校的哮喘计划已显示出在该人群中控制哮喘的有前景的结果。