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当代血管内腹主动脉瘤修复中 IIIB 型内漏导致支架移植物失败的发生率。

Incidence of stent graft failure from type IIIB endoleak in contemporary endovascular abdominal aortic aneurysm repair.

机构信息

Westchester Medical Center, New York Medical College, Valhalla, NY.

Division of Endovascular and Vascular Surgery, Thomas Jefferson University Hospital, Philadelphia, Pa.

出版信息

J Vasc Surg. 2020 Feb;71(2):645-653. doi: 10.1016/j.jvs.2019.06.183. Epub 2019 Aug 26.

DOI:10.1016/j.jvs.2019.06.183
PMID:31466740
Abstract

BACKGROUND

Type IIIB endoleak from material failure can lead to aneurysmal sac enlargement and latent rupture after endovascular repair of abdominal aortic aneurysm. Long-term durability of the endovascular stent graft is largely unknown, and the complication rate from device failure due to material fatigue may be underappreciated. In addition, even with advancement in imaging techniques, recognition of type IIIB endoleak can be challenging, which can lead to delay in intervention.

METHODS

A review of the literature was performed in PubMed and Google Scholar, yielding 23 articles with 46 case reports of type IIIB endoleak from various Food and Drug Administration-approved stent grafts after endovascular repair of infrarenal abdominal aortic aneurysm.

RESULTS

The most common location of type IIIB endoleak occurred in the main body (34.8%), followed by the area of the flow divider (32.6%). Sac growth was identified in 63% (29/46) of cases. Diagnosis of the endoleak occurred an average of 54.3 months after the index operation. Endovascular repair was the primary approach for elective repair of type IIIB endoleak (61.3% vs 13.3%). Perioperative mortality was higher in ruptured or symptomatic patients compared with patients undergoing elective repair (33.3% vs 6.5%).

CONCLUSIONS

The actual incidence of type IIIB endoleak is still lacking, and the etiology may be multifactorial. Therefore, suspicion of type IIIB endoleak requires appropriate imaging techniques and prompt intervention to reduce the perioperative mortality rate.

摘要

背景

IIIb 型内漏源于材料失效,可导致腹主动脉瘤血管内修复后瘤囊扩大和潜在破裂。血管内支架移植物的长期耐用性很大程度上未知,且因材料疲劳导致器械失效的并发症发生率可能被低估。此外,即使影像学技术有所进步,IIIb 型内漏的识别仍具有挑战性,这可能导致介入延迟。

方法

在 PubMed 和 Google Scholar 中进行文献回顾,共检索到 23 篇文章,其中包括 46 例源自各种经美国食品和药物管理局批准的支架移植物的 IIIb 型内漏病例报告,这些病例均来自腹主动脉瘤肾下型血管内修复术后。

结果

IIIb 型内漏最常见的部位是主体(34.8%),其次是分流器区域(32.6%)。63%(29/46)的病例存在瘤囊生长。内漏的诊断平均发生在指数手术后 54.3 个月。血管内修复是 IIIB 型内漏择期修复的主要方法(61.3%比 13.3%)。与择期修复的患者相比,破裂或有症状的患者围手术期死亡率更高(33.3%比 6.5%)。

结论

IIIb 型内漏的实际发生率仍不清楚,病因可能是多因素的。因此,对 IIIb 型内漏的怀疑需要适当的影像学技术和及时的干预,以降低围手术期死亡率。

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