Early high plasma ST2, the decoy IL-33 receptor, in children undergoing hematopoietic cell transplantation is associated with the development of post-transplant diabetes mellitus.
作者信息
Rowan Courtney M, Teagarden Alicia M, Cater Daniel T, Moser Elizabeth A S, Baykoyannis Giorgos, Paczesny Sophie
机构信息
Department of Pediatrics, Indiana University School of Medicine
Department of Pediatrics, Indiana University School of Medicine.
出版信息
Haematologica. 2020 May;105(5):e249-e252. doi: 10.3324/haematol.2019.222992. Epub 2019 Aug 29.
Abstract
摘要
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Early high plasma ST2, the decoy IL-33 receptor, in children undergoing hematopoietic cell transplantation is associated with the development of post-transplant diabetes mellitus.造血细胞移植患儿早期血浆中高水平的可溶性ST2（诱饵型白细胞介素-33受体）与移植后糖尿病的发生有关。
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本文引用的文献
1
New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications.异基因造血细胞移植后新发移植后糖尿病的发生是由胰岛素抵抗引起的，而不是免疫抑制药物。
Biol Blood Marrow Transplant. 2019 Jun;25(6):1225-1231. doi: 10.1016/j.bbmt.2019.02.001. Epub 2019 Feb 7.
2
Metabolic Complications Precede Alloreactivity and Are Characterized by Changes in Suppression of Tumorigenicity 2 Signaling.代谢并发症先于同种异体反应性出现，并以致瘤性2信号抑制的变化为特征。
Biol Blood Marrow Transplant. 2017 Mar;23(3):529-532. doi: 10.1016/j.bbmt.2016.12.627. Epub 2016 Dec 21.
3
Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes.炎症作为肥胖、代谢综合征和 2 型糖尿病之间的联系。
Diabetes Res Clin Pract. 2014 Aug;105(2):141-50. doi: 10.1016/j.diabres.2014.04.006. Epub 2014 Apr 13.
4
ST2 as a marker for risk of therapy-resistant graft-versus-host disease and death.ST2 可作为治疗抵抗性移植物抗宿主病和死亡的标志物。
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5
Toll/interleukin-1 receptor member ST2 exhibits higher soluble levels in type 2 diabetes, especially when accompanied with left ventricular diastolic dysfunction.Toll/白介素-1 受体成员 ST2 的可溶性水平在 2 型糖尿病中较高，尤其是伴有左心室舒张功能障碍时。
Cardiovasc Diabetol. 2011 Nov 21;10:101. doi: 10.1186/1475-2840-10-101.
6
Pretransplantation C-Peptide level predicts early posttransplantation diabetes mellitus and has an impact on survival after allogeneic stem cell transplantation.移植前 C 肽水平可预测移植后早期糖尿病，并对异基因干细胞移植后的生存产生影响。
Biol Blood Marrow Transplant. 2011 Jan;17(1):86-92. doi: 10.1016/j.bbmt.2010.06.010. Epub 2010 Jun 16.
7
Hyperglycemia during the neutropenic period is associated with a poor outcome in patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation.在接受清髓性异基因造血干细胞移植的患者中，中性粒细胞减少期的高血糖与不良预后相关。
Transplantation. 2007 Oct 15;84(7):814-20. doi: 10.1097/01.tp.0000296482.50994.1c.
8
Adverse clinical consequences of hyperglycemia from total parenteral nutrition exposure during hematopoietic stem cell transplantation.造血干细胞移植期间全肠外营养暴露导致高血糖的不良临床后果。
Biol Blood Marrow Transplant. 2006 Jun;12(6):656-64. doi: 10.1016/j.bbmt.2006.01.010.
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