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Extending corneal storage with 2.5% chondroitin sulfate (K-Sol).

作者信息

Keates R H, Rabin B

机构信息

Department of Ophthalmology, Ohio State University, Columbus 43210.

出版信息

Ophthalmic Surg. 1988 Nov;19(11):817-20. doi: 10.3928/0090-4481-19881101-13.

DOI:10.3928/0090-4481-19881101-13
PMID:3146744
Abstract

K-Sol corneal storage medium maintains corneal viability for at least ten days, compared with McCarey-Kaufman (M-K) medium, which does so for a reported maximum of three days. Since many eye banks still use M-K medium exclusively, stored corneas must be used without undue delay, and shipping time further hastens the planned surgery time. Transferring the shipped M-K medium-stored cornea to K-Sol offers a simple way of increasing storage time in our eye bank. Ninety-five out of 100 transferred corneas (95%) remained clear 3 to 18 months postoperatively. There were no primary graft failures, and transferred corneal mates were clear. A comparable series of 100 corneas stored in M-K medium alone, or in K-Sol alone, were clear in 93% and 97% of the transplants. Analysis of donor rims after keratoplasty indicated statistically significantly more endothelial cell loss during storage in corneas transferred to K-Sol compared with 18 corneas preserved only in M-K medium for a similar length of time. There was no statistical significance between the transferred group and the group preserved in only K-Sol. Transferring M-K medium stored corneas to K-Sol medium may be a useful means of extending corneal storage time, resulting in improved tissue utilization.

摘要

相似文献

1
Extending corneal storage with 2.5% chondroitin sulfate (K-Sol).
Ophthalmic Surg. 1988 Nov;19(11):817-20. doi: 10.3928/0090-4481-19881101-13.
2
Comparison of corneal storage in K-Sol and chondroitin sulfate corneal storage medium in human corneal transplantation.K-Sol与硫酸软骨素角膜保存介质在人类角膜移植中角膜保存的比较。
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4
Results of transplantation of corneas preserved in 2.5% chondroitin sulfate.
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Comparison of K-Sol and M-K medium for cornea storage: results of penetrating keratoplasty in rabbits.用于角膜储存的K-Sol和M-K培养基的比较:兔穿透性角膜移植术的结果
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7
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K-Sol corneal preservation.
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Recent advances in preservation of viable corneal tissue.活性角膜组织保存的最新进展
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