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用于角膜储存的K-Sol和M-K培养基的比较:兔穿透性角膜移植术的结果

Comparison of K-Sol and M-K medium for cornea storage: results of penetrating keratoplasty in rabbits.

作者信息

Busin M, Yau C W, Avni I, Kaufman H E

出版信息

Br J Ophthalmol. 1986 Nov;70(11):860-3. doi: 10.1136/bjo.70.11.860.

Abstract

Five pairs of rabbit corneas were stored for two weeks at 4 degrees C, one of each pair in K-Sol medium, and one in McCarey-/Kaufman (M-K) medium. After transplantation all penetrating keratoplasty grafts became clear and thin. Endothelial cell loss was significantly less in the K-Sol stored corneas. Another five pairs of corneas were stored for two weeks in K-Sol or three days in M-K medium. After penetrating keratoplasty there were no significant differences in clarity, thickness, or endothelial cell loss. The results indicate that K-Sol provides satisfactory medium-term corneal storage compared with short-term storage in M-K medium at refrigerator temperatures.

摘要

五对兔角膜在4摄氏度下保存两周,每对中的一只置于K-Sol培养基中,另一只置于麦卡里 - 考夫曼(M-K)培养基中。移植后,所有穿透性角膜移植片均变得清晰且变薄。在K-Sol保存的角膜中,内皮细胞损失明显较少。另外五对角膜在K-Sol中保存两周或在M-K培养基中保存三天。穿透性角膜移植术后,在透明度、厚度或内皮细胞损失方面没有显著差异。结果表明,与在冰箱温度下在M-K培养基中短期保存相比,K-Sol提供了令人满意的中期角膜保存效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b2c/1040843/01c377a091ea/brjopthal00131-0065-a.jpg

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