Marsan Marco, Lucidi Massimiliano, Pudda Francesco, Pirolo Mattia, Frangipani Emanuela, Visca Paolo, Cincotti Gabriella
Engineering Department, University Roma Tre, via Vito Volterra 62, 00146 Rome, Italy.
Department of Science, University Roma Tre, viale Marconi 446, 00146 Rome, Italy.
Biomed Opt Express. 2019 Jun 26;10(7):3654-3662. doi: 10.1364/BOE.10.003654. eCollection 2019 Jul 1.
A geometrical-optics approach is proposed to increase the accuracy in photometric measurements, using a point-of-care testing (POCT) LED-based sensor. Due to stray-light effects, the measurement accuracy depends on the dimension of the CMOS area, where the radiation is detected. We propose two image processing approaches and evaluate the influence of the sensor area. In addition, we demonstrate that with the same measurement, both absorption coefficient and refractive index can be determined, measuring the beam attenuation and the spot-size enlargement due to ray refraction.
提出了一种几何光学方法，以提高基于即时检验（POCT）发光二极管的传感器光度测量的准确性。由于杂散光效应，测量精度取决于检测辐射的互补金属氧化物半导体（CMOS）区域的尺寸。我们提出了两种图像处理方法，并评估了传感器面积的影响。此外，我们证明，在相同测量中，通过测量光束衰减和光线折射导致的光斑尺寸增大，可以确定吸收系数和折射率。
