Peripheral Blood Gene Expression Signatures of Eosinophilic Chronic Obstructive Pulmonary Disease.
作者信息
Yun Jeong H, Chase Robert, Parker Margaret M, Saferali Aabida, Castaldi Peter J, Silverman Edwin K, Hersh Craig P
机构信息
Brigham and Women's HospitalBoston, Massachusettsand.
Harvard Medical SchoolBoston, Massachusetts.
出版信息
Am J Respir Cell Mol Biol. 2019 Sep;61(3):398-401. doi: 10.1165/rcmb.2019-0112LE.
Abstract
摘要
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Modulation of blood inflammatory markers by benralizumab in patients with eosinophilic airway diseases.贝那利珠单抗对嗜酸性气道疾病患者血液炎症标志物的调节作用。
Respir Res. 2019 Jan 18;20(1):14. doi: 10.1186/s12931-018-0968-8.
2
Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease.慢性阻塞性肺疾病患者的血嗜酸性粒细胞计数阈值与加重。
J Allergy Clin Immunol. 2018 Jun;141(6):2037-2047.e10. doi: 10.1016/j.jaci.2018.04.010. Epub 2018 Apr 28.
3
RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking.RNA测序鉴定出与吸烟相关的新型非编码RNA和外显子特异性效应。
BMC Med Genomics. 2017 Oct 6;10(1):58. doi: 10.1186/s12920-017-0295-9.
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Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease.美泊利珠单抗治疗嗜酸性粒细胞性慢性阻塞性肺疾病。
N Engl J Med. 2017 Oct 26;377(17):1613-1629. doi: 10.1056/NEJMoa1708208. Epub 2017 Sep 11.
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Eosinophils in COPD: just another biomarker?COPD 中的嗜酸性粒细胞：仅仅是另一种生物标志物吗？
Lancet Respir Med. 2017 Sep;5(9):747-759. doi: 10.1016/S2213-2600(17)30217-5. Epub 2017 Jun 7.
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