Department of Neurosurgery, Mayo Clinic Florida, Jacksonville, Florida, USA.
Department of Neurosurgery, University of Illinois College of Medicine at Chicago, Chicago, Illinois, USA.
World Neurosurg. 2020 Feb;134:e16-e28. doi: 10.1016/j.wneu.2019.08.121. Epub 2019 Aug 27.
Flow diversion has become increasingly popular for treatment of cerebral aneurysms in the past few years. In an increasing number of patients with aneurysms, flow diversion (FD) has failed, with a paucity of reported data regarding salvage treatment for these challenging cases.
We present a multicenter series of 13 aneurysms for which FD failed and that were subsequently treated with open surgery. We also present a review of the reported data regarding operative management of aneurysms after unsuccessful FD.
Twelve patients with 13 aneurysms were included in the present study. All 12 patients had undergone surgery after FD because of persistent aneurysm filling, mass effect, or aneurysm rupture. The patients underwent aneurysm clipping and parent vessel reconstruction, decompression of the aneurysm mass, occlusion of proximal flow to the aneurysm, or aneurysm trapping with or without extracranial-intracranial artery bypass.
Aneurysms for which FD fails present a variety of unique and challenging management situations that will likely be encountered with increased frequency, given the popularity of FD. Microsurgical salvage options require individualized care tailored to the underlying pathological features, patient characteristics, and surgical expertise.
在过去的几年中,血流导向装置(Flow diversion)已越来越多地用于治疗颅内动脉瘤。在越来越多的动脉瘤患者中,血流导向装置治疗失败,而对于这些具有挑战性的病例,缺乏关于挽救治疗的报告数据。
我们提出了一个多中心系列研究,共纳入 13 例血流导向装置治疗失败的动脉瘤患者,这些患者随后接受了开放性手术治疗。我们还回顾了关于血流导向装置治疗失败后手术治疗动脉瘤的报告数据。
本研究共纳入 12 例患者的 13 个动脉瘤。所有 12 例患者均因持续的动脉瘤填充、占位效应或动脉瘤破裂而行 FD 后手术。患者接受了动脉瘤夹闭和载瘤动脉重建、动脉瘤肿块减压、近端血流闭塞至动脉瘤、或夹闭动脉瘤伴或不伴颅内外动脉旁路。
血流导向装置治疗失败的动脉瘤呈现出各种独特而具有挑战性的治疗情况,鉴于血流导向装置的广泛应用,这些情况可能会越来越频繁地遇到。需要根据潜在的病理特征、患者特征和手术专业知识,为每个患者制定个体化的显微外科挽救治疗方案。