Oh Woo Taek, Giri Sib Sankar, Yun Saekil, Kim Hyoun Joong, Kim Sang Guen, Kim Sang Wha, Kang Jeong Woo, Han Se Jin, Kwon Jun, Jun Jin Woo, Park Se Chang
Laboratory of Aquatic Biomedicine, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Department of Aquaculture, Korea National College of Agriculture and Fisheries, Jeonju 54874, Korea.
Microorganisms. 2019 Aug 29;7(9):302. doi: 10.3390/microorganisms7090302.
Red mark syndrome (RMS) is a fish disease caused by the infection of Rickettsial agents, especially affecting rainbow trout (. The disease is prevalent in many countries in Europe (France, Switzerland, Italy, and Slovenia), South America (Chile), North America (USA), and even Asia (Japan). However, it has not been reported in Korean aquaculture. In February 2019, rainbow trout presenting red spot lesions with swollen features on the lateral side of their body were observed at a hatchery in Korea. Fishes showing those clinical signs were fry weighing 25 ± 5 g. Moreover, the fish showing the red spot lesions were found dead, which suggests an outbreak of a mortality-causing disease. The symptoms were similar to those of RMS, and we identified the presence of -like organisms associated with this disease using polymerase chain reaction (PCR), sequencing, histopathologic examination, and transmission electron microscopy. The distinct features of this infection, compared to that in previous reports, were that RMS occurred in small-sized fish and accompanied mortality. Additionally, the presence of the agent was accompanied with outbreak of the disease. Therefore, this is the first report of RMS outbreak in rainbow trout fisheries in Korea.
红斑综合征（RMS）是一种由立克次氏体感染引起的鱼类疾病，尤其影响虹鳟鱼（ ）。该病在欧洲的许多国家（法国、瑞士、意大利和斯洛文尼亚）、南美洲（智利）、北美洲（美国）甚至亚洲（日本）都很普遍。然而，韩国水产养殖中尚未有相关报道。2019年2月，在韩国的一个孵化场观察到虹鳟鱼身体侧面出现有肿胀特征的红斑病变。出现这些临床症状的鱼是体重为25±5克的鱼苗。此外，发现出现红斑病变的鱼死亡，这表明爆发了一种导致死亡的疾病。症状与RMS相似，我们通过聚合酶链反应（PCR）、测序、组织病理学检查和透射电子显微镜鉴定出与该疾病相关的类生物的存在。与之前的报道相比，这种感染的独特特征是RMS发生在小型鱼身上并伴有死亡。此外，病原体的存在伴随着疾病的爆发。因此，这是韩国虹鳟渔业中RMS爆发的首次报道。
