Leandri Chloé, Guillaumot Marie-Anne, Dohan Anthony, Leconte Mahaut, Coriat Romain, Chaussade Stanislas, Barret Maximilien
Hôpital Cochin, service de gastro-entérologie et oncologie digestive, 27, rue du Faubourg St Jacques, 75014 Paris, France.
Hôpital Cochin, service de gastro-entérologie et oncologie digestive, 27, rue du Faubourg St Jacques, 75014 Paris, France; Faculté Paris Descartes, 75006 Paris, France.
Presse Med. 2019 Sep;48(9):897-903. doi: 10.1016/j.lpm.2019.07.012. Epub 2019 Aug 27.
Ineffective esophageal motility is the most frequent esophageal motility disorder. It is currently defined by 50% or more ineffective esophageal contractions and a normal lower esophageal sphincter relaxation on high-resolution esophageal manometry. Although reported in patients without symptoms, it is typically associated with gastro-esophageal reflux disease, and might be a consequence of the reflux. Ineffective esophageal motility can account for a certain degree of dysphagia, and is associated with a more severe gastroesophageal reflux. Todate, no specific endoscopic or pharmacologic treatment is available, and proton pump inhibitor are advisable when gastro-esophageal reflux is associated.
无效食管动力是最常见的食管动力障碍。目前,在高分辨率食管测压中,其定义为50%或更多的食管收缩无效且食管下括约肌松弛正常。尽管在无症状患者中也有报道,但它通常与胃食管反流病相关,可能是反流的结果。无效食管动力可导致一定程度的吞咽困难,并与更严重的胃食管反流相关。迄今为止,尚无特定的内镜或药物治疗方法,当合并胃食管反流时,建议使用质子泵抑制剂。